{"version":"1.0","provider_name":"Glossary","provider_url":"https:\/\/www.healthbenefitstimes.com\/glossary","author_name":"Glossary","author_url":"https:\/\/www.healthbenefitstimes.com\/glossary\/author\/adminglossary\/","title":"Endoplasmic reticulum (ER) - Definition of Endoplasmic reticulum (ER)","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"J8D8Kx1F3D\"><a href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/endoplasmic-reticulum-er\/\">Endoplasmic reticulum (ER)<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.healthbenefitstimes.com\/glossary\/endoplasmic-reticulum-er\/embed\/#?secret=J8D8Kx1F3D\" width=\"600\" height=\"338\" title=\"&#8220;Endoplasmic reticulum (ER)&#8221; &#8212; Glossary\" data-secret=\"J8D8Kx1F3D\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/www.healthbenefitstimes.com\/glossary\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","description":"A highly specialized, complex network of branching, intercommunicating tubules (surrounded by membranes) found in the cytoplasm of most animal and plant cells. The two types of ER recognized are: the rough ER and smooth ER. ER that is covered with many ribosomes is called rough and the ER without or with fewer ribosomes attached is called smooth. This nomenclature comes about because of the appearance of the ER under high magnification. The rough ER is very well developed to facilitate cells carrying on abundant protein synthesis.Endomembrane system, in which many proteins are modified posttrans-lationally.An intracellular system of membranous channels that transport materials throughout the cell. Smooth has no ribosomes attached to it, while rough does.A network of microscopic channels or tubes extending throughout the cytoplasm that serves as a transport system for materials within the cell.A system of membranes present in the cytoplasm of cells. ER is described as rough when it has ribosomes attached to its surface and smooth when ribosomes are absent. It is the site of manufacture of proteins and lipids and is concerned with the transport of these products within the cell.A cell organelle that is a complex network of membranous tubules in the cytoplasm between the nuclear and cell membranes; it is visible only with an electron microscope. One form with ribosomes attached is called granular or rough ER; another form that is free of ribosomes is called agranular or smooth ER. Rough ER transports proteins produced on the ribosomes; smooth ER synthesizes lipids."}