{"version":"1.0","provider_name":"Glossary","provider_url":"https:\/\/www.healthbenefitstimes.com\/glossary","author_name":"Glossary","author_url":"https:\/\/www.healthbenefitstimes.com\/glossary\/author\/adminglossary\/","title":"Folacin - Definition of Folacin","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"e5Qyj9CUe3\"><a href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/folacin\/\">Folacin<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.healthbenefitstimes.com\/glossary\/folacin\/embed\/#?secret=e5Qyj9CUe3\" width=\"600\" height=\"338\" title=\"&#8220;Folacin&#8221; &#8212; Glossary\" data-secret=\"e5Qyj9CUe3\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/www.healthbenefitstimes.com\/glossary\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","description":"An older term for the B vitamin folic acid or folate. Folacin plays an important role in cell reproduction and has a protective effect against a variety of disorders, especially birth defects. Good sources of folacin include dried beans and peas, green vegetables, oranges, whole grains, and fortified grain products.A member of the vitamin B complex group is necessary for cell growth and reproduction. A deficiency can result in megaloblastic anemia is a water-soluble vitamin.An essential B vitamin that participates in one-carbon transfer. Folic acid (folate or folacin) is the generic term for pteroylmonoglutamic acid and its related biologically active compounds. A number of derivatives have vitamin activity. The derivatives include the addition of hydrogen at N5 and N10 and only one glutamate attached to para-aminobenzoic acid. This derivative is called tetrahydrofolic acid (THF). Other derivatives can have a methyl group attached at N5, a methyl bridge between N5 and NIO or a methylene bridge at this position or an aldehyde group at either N5 or N10 or a HCNH group at N5. All of these derivatives have vitamin activity because vitamin activity is dependent on the presence of a pterin structure with variable hydrogenation or methyl addition at N5 or N10 and the presence of at least one glutamyl residue linked via peptide bonds to p-aminobenzoic acid. Methotrexate (4-amino-N10-methyl folic acid, an antineoplastic agent) and aminopterin (4-amino folic acid, a rodenticide) are folate antagonists and as such are useful pharmaceutical agents against cell growth. Folacin is an orange-yellow crystal with a melting point of 250\u00b0C. It is unstable to ultraviolet light, heat, oxygen, acid conditions, and divalent metal ions such as iron and copper."}