{"version":"1.0","provider_name":"Glossary","provider_url":"https:\/\/www.healthbenefitstimes.com\/glossary","author_name":"Glossary","author_url":"https:\/\/www.healthbenefitstimes.com\/glossary\/author\/adminglossary\/","title":"Nanocrystal molecules - Definition of Nanocrystal molecules","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"Sfj1LZpEOc\"><a href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/nanocrystal-molecules\/\">Nanocrystal molecules<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.healthbenefitstimes.com\/glossary\/nanocrystal-molecules\/embed\/#?secret=Sfj1LZpEOc\" width=\"600\" height=\"338\" title=\"&#8220;Nanocrystal molecules&#8221; &#8212; Glossary\" data-secret=\"Sfj1LZpEOc\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/www.healthbenefitstimes.com\/glossary\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","description":"Coined by researchers A. Paul Alivisatos and Peter G. Schultz, it is a term used to describe double-stranded DNA molecules that have attached to them several multi-atom clusters of gold. As of 1 996, these researchers were working to try to create nanometerscale electrical circuits, semiconductors, etc.A separate methodology, researched by Chad A. Mirkin et al., utilizes strands of DNA to reversibly assemble gold nanoparticles (nanometer-scale multi-atom particles) into supramolecular (many molecule) agglomerations, in which the gold particles are separated from each other by a distance of approximately 60 Angstroms. The aggregation of these DNA-metal nanoparticles causes a visible color change to occur. As of 1996, these researchers were working to try to create simple and rapid tests that would indicate the presence of a virus (e.g., HIV-1 or HIV-2) via a visible color change. Such a test would use two noncomplementary DNA sequences, each of which has attached to it a gold nanoparticle (via a thiol group). The two sequences would be selected for their ability to latch onto a target sequence in the desired virus, but they would be unable to combine with each other, since they are noncomplementary. When double-stranded DNA molecules possessing two \"sticky ends\" (that are complementary to the sequences attached to virus) are added, the resultant color change indicates virus presence."}