{"id":107607,"date":"2021-05-21T08:21:10","date_gmt":"2021-05-21T08:21:10","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=107607"},"modified":"2023-08-31T09:55:06","modified_gmt":"2023-08-31T09:55:06","slug":"thiazolidinedione","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/thiazolidinedione\/","title":{"rendered":"Thiazolidinedione"},"content":{"rendered":"<p>A drug that decreases insulin resistance, increases muscle glucose use, decreases gluconeogenesis, increases PPAR\u03b3 in adipose tissue, and leads to an increase in fatty acid uptake by the adipose tissue.<\/p>\n<hr \/>\n<p>A class of oral hypoglycemic agents that lowers blood sugars by reducing insulin resistance (improving tissue sensitivity to the effects of insulin) in fat and muscle, as well as the liver. A commonly used agent in this class is pioglitazone.<\/p>\n<hr \/>\n<div class=\"group w-full text-token-text-primary border-b border-black\/10 dark:border-gray-900\/50 bg-gray-50 dark:bg-[#444654]\" data-testid=\"conversation-turn-131\">\n<div class=\"p-4 justify-center text-base md:gap-6 md:py-6 lg:px-0 m-auto\">\n<div class=\"flex flex-1 gap-4 text-base mx-auto md:gap-6 md:max-w-2xl lg:max-w-[38rem] xl:max-w-3xl }\">\n<div class=\"relative flex w-[calc(100%-50px)] flex-col gap-1 md:gap-3 lg:w-[calc(100%-115px)]\">\n<div class=\"flex flex-grow flex-col gap-3 max-w-full\">\n<div class=\"min-h-[20px] flex flex-col items-start gap-3 overflow-x-auto whitespace-pre-wrap break-words\">\n<div class=\"markdown prose w-full break-words dark:prose-invert light\">\n<p>Also known as glitazones, thiazolidinediones are a class of oral hypoglycemic medications employed for managing type 2 diabetes mellitus. These drugs function by diminishing the body cells&#8217; resistance to insulin and are frequently utilized alongside other oral hypoglycemic agents like metformin or a sulfonylurea drug. The primary thiazolidinediones are pioglitazone and rosiglitazone.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A drug that decreases insulin resistance, increases muscle glucose use, decreases gluconeogenesis, increases PPAR\u03b3 in adipose tissue, and leads to an increase in fatty acid uptake by the adipose tissue. A class of oral hypoglycemic agents that lowers blood sugars by reducing insulin resistance (improving tissue sensitivity to the effects of insulin) in fat and [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-107607","post","type-post","status-publish","format-standard","hentry","category-t"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Thiazolidinedione - Definition of Thiazolidinedione<\/title>\n<meta name=\"description\" content=\"A drug that decreases insulin resistance, increases muscle glucose use, decreases gluconeogenesis, increases PPAR\u03b3 in adipose tissue, and leads to an increase in fatty acid uptake by the adipose tissue.A class of oral hypoglycemic agents that lowers blood sugars by reducing insulin resistance (improving tissue sensitivity to the effects of insulin) in fat and muscle, as well as the liver. A commonly used agent in this class is pioglitazone.Also known as glitazones, thiazolidinediones are a class of oral hypoglycemic medications employed for managing type 2 diabetes mellitus. These drugs function by diminishing the body cells&#039; resistance to insulin and are frequently utilized alongside other oral hypoglycemic agents like metformin or a sulfonylurea drug. The primary thiazolidinediones are pioglitazone and rosiglitazone.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/thiazolidinedione\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Thiazolidinedione - Definition of Thiazolidinedione\" \/>\n<meta property=\"og:description\" content=\"A drug that decreases insulin resistance, increases muscle glucose use, decreases gluconeogenesis, increases PPAR\u03b3 in adipose tissue, and leads to an increase in fatty acid uptake by the adipose tissue.A class of oral hypoglycemic agents that lowers blood sugars by reducing insulin resistance (improving tissue sensitivity to the effects of insulin) in fat and muscle, as well as the liver. A commonly used agent in this class is pioglitazone.Also known as glitazones, thiazolidinediones are a class of oral hypoglycemic medications employed for managing type 2 diabetes mellitus. These drugs function by diminishing the body cells&#039; resistance to insulin and are frequently utilized alongside other oral hypoglycemic agents like metformin or a sulfonylurea drug. The primary thiazolidinediones are pioglitazone and rosiglitazone.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.healthbenefitstimes.com\/glossary\/thiazolidinedione\/\" \/>\n<meta property=\"og:site_name\" content=\"Glossary\" \/>\n<meta property=\"article:published_time\" content=\"2021-05-21T08:21:10+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-08-31T09:55:06+00:00\" \/>\n<meta name=\"author\" content=\"Glossary\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Glossary\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/thiazolidinedione\/\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/thiazolidinedione\/\",\"name\":\"Thiazolidinedione - Definition of Thiazolidinedione\",\"isPartOf\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\"},\"datePublished\":\"2021-05-21T08:21:10+00:00\",\"dateModified\":\"2023-08-31T09:55:06+00:00\",\"author\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\"},\"description\":\"A drug that decreases insulin resistance, increases muscle glucose use, decreases gluconeogenesis, increases PPAR\u03b3 in adipose tissue, and leads to an increase in fatty acid uptake by the adipose tissue.A class of oral hypoglycemic agents that lowers blood sugars by reducing insulin resistance (improving tissue sensitivity to the effects of insulin) in fat and muscle, as well as the liver. A commonly used agent in this class is pioglitazone.Also known as glitazones, thiazolidinediones are a class of oral hypoglycemic medications employed for managing type 2 diabetes mellitus. These drugs function by diminishing the body cells' resistance to insulin and are frequently utilized alongside other oral hypoglycemic agents like metformin or a sulfonylurea drug. 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A commonly used agent in this class is pioglitazone.Also known as glitazones, thiazolidinediones are a class of oral hypoglycemic medications employed for managing type 2 diabetes mellitus. These drugs function by diminishing the body cells' resistance to insulin and are frequently utilized alongside other oral hypoglycemic agents like metformin or a sulfonylurea drug. 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