{"id":108288,"date":"2021-05-25T07:04:37","date_gmt":"2021-05-25T07:04:37","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=108288"},"modified":"2022-04-12T07:03:56","modified_gmt":"2022-04-12T07:03:56","slug":"alexander-disease","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/alexander-disease\/","title":{"rendered":"Alexander disease"},"content":{"rendered":"<p>Alexander disease is a rare, genetic, degenerative disorder of the nervous system. It is one of a group of genetic disorders called the leukodystrophies that affect growth of the myelin sheath on nerve fibers in the brain. The myelin sheath is the fatty covering that acts as an insulator.<\/p>\n<hr \/>\n<p>A rare neurodegenerative disorder characterized by early onset dementia or encephalopathy and muscular spasticity. It usually results from a mutation in the gene that codes for glial fibrillary acidic protein (GFAP). Brain specimens from affected patients show the accumulation of abnormal inclusion bodies within astrocytes.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alexander disease is a rare, genetic, degenerative disorder of the nervous system. It is one of a group of genetic disorders called the leukodystrophies that affect growth of the myelin sheath on nerve fibers in the brain. The myelin sheath is the fatty covering that acts as an insulator. A rare neurodegenerative disorder characterized by [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-108288","post","type-post","status-publish","format-standard","hentry","category-a"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Alexander disease - Definition of Alexander disease<\/title>\n<meta name=\"description\" content=\"Alexander disease is a rare, genetic, degenerative disorder of the nervous system. It is one of a group of genetic disorders called the leukodystrophies that affect growth of the myelin sheath on nerve fibers in the brain. The myelin sheath is the fatty covering that acts as an insulator.A rare neurodegenerative disorder characterized by early onset dementia or encephalopathy and muscular spasticity. It usually results from a mutation in the gene that codes for glial fibrillary acidic protein (GFAP). Brain specimens from affected patients show the accumulation of abnormal inclusion bodies within astrocytes.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/alexander-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Alexander disease - Definition of Alexander disease\" \/>\n<meta property=\"og:description\" content=\"Alexander disease is a rare, genetic, degenerative disorder of the nervous system. It is one of a group of genetic disorders called the leukodystrophies that affect growth of the myelin sheath on nerve fibers in the brain. The myelin sheath is the fatty covering that acts as an insulator.A rare neurodegenerative disorder characterized by early onset dementia or encephalopathy and muscular spasticity. It usually results from a mutation in the gene that codes for glial fibrillary acidic protein (GFAP). Brain specimens from affected patients show the accumulation of abnormal inclusion bodies within astrocytes.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.healthbenefitstimes.com\/glossary\/alexander-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"Glossary\" \/>\n<meta property=\"article:published_time\" content=\"2021-05-25T07:04:37+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-04-12T07:03:56+00:00\" \/>\n<meta name=\"author\" content=\"Glossary\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Glossary\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/alexander-disease\/\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/alexander-disease\/\",\"name\":\"Alexander disease - Definition of Alexander disease\",\"isPartOf\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\"},\"datePublished\":\"2021-05-25T07:04:37+00:00\",\"dateModified\":\"2022-04-12T07:03:56+00:00\",\"author\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\"},\"description\":\"Alexander disease is a rare, genetic, degenerative disorder of the nervous system. 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