{"id":108901,"date":"2021-05-27T10:46:29","date_gmt":"2021-05-27T10:46:29","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=108901"},"modified":"2021-05-27T10:46:29","modified_gmt":"2021-05-27T10:46:29","slug":"leigh-syndrome","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/","title":{"rendered":"Leigh syndrome"},"content":{"rendered":"

Leigh Syndrome, also termed subacute necrotizing encephalomyelopathy, presents as a progressive neurometabolic disorder and often results from mitochondrial DNA mutation. Such mutations disrupt the mitochondria\u2019s ability to produce the cellular energy. Furthermore, the central nervous system appears to be most directly affected by mitochondrial dysfunction. The onset of Leigh syndrome is usually prior to 2 years of age, and although onset in adolescence and early adulthood is possible, it is rare (National Institute of Neurological Disorders and Stroke [NINDS], 2001).<\/p>\n

\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Leigh Syndrome, also termed subacute necrotizing encephalomyelopathy, presents as a progressive neurometabolic disorder and often results from mitochondrial DNA mutation. Such mutations disrupt the mitochondria\u2019s ability to produce the cellular energy. Furthermore, the central nervous system appears to be most directly affected by mitochondrial dysfunction. The onset of Leigh syndrome is usually prior to 2 […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12],"tags":[],"class_list":["post-108901","post","type-post","status-publish","format-standard","hentry","category-l"],"yoast_head":"\nLeigh syndrome - Definition of Leigh syndrome<\/title>\n<meta name=\"description\" content=\"Leigh Syndrome, also termed subacute necrotizing encephalomyelopathy, presents as a progressive neurometabolic disorder and often results from mitochondrial DNA mutation. Such mutations disrupt the mitochondria\u2019s ability to produce the cellular energy. Furthermore, the central nervous system appears to be most directly affected by mitochondrial dysfunction. The onset of Leigh syndrome is usually prior to 2 years of age, and although onset in adolescence and early adulthood is possible, it is rare (National Institute of Neurological Disorders and Stroke [NINDS], 2001).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Leigh syndrome - Definition of Leigh syndrome\" \/>\n<meta property=\"og:description\" content=\"Leigh Syndrome, also termed subacute necrotizing encephalomyelopathy, presents as a progressive neurometabolic disorder and often results from mitochondrial DNA mutation. Such mutations disrupt the mitochondria\u2019s ability to produce the cellular energy. Furthermore, the central nervous system appears to be most directly affected by mitochondrial dysfunction. The onset of Leigh syndrome is usually prior to 2 years of age, and although onset in adolescence and early adulthood is possible, it is rare (National Institute of Neurological Disorders and Stroke [NINDS], 2001).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/\" \/>\n<meta property=\"og:site_name\" content=\"Glossary\" \/>\n<meta property=\"article:published_time\" content=\"2021-05-27T10:46:29+00:00\" \/>\n<meta name=\"author\" content=\"Glossary\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Glossary\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/\",\"name\":\"Leigh syndrome - Definition of Leigh syndrome\",\"isPartOf\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\"},\"datePublished\":\"2021-05-27T10:46:29+00:00\",\"dateModified\":\"2021-05-27T10:46:29+00:00\",\"author\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\"},\"description\":\"Leigh Syndrome, also termed subacute necrotizing encephalomyelopathy, presents as a progressive neurometabolic disorder and often results from mitochondrial DNA mutation. Such mutations disrupt the mitochondria\u2019s ability to produce the cellular energy. Furthermore, the central nervous system appears to be most directly affected by mitochondrial dysfunction. The onset of Leigh syndrome is usually prior to 2 years of age, and although onset in adolescence and early adulthood is possible, it is rare (National Institute of Neurological Disorders and Stroke [NINDS], 2001).\",\"breadcrumb\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Leigh syndrome\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/\",\"name\":\"Glossary\",\"description\":\"Difinitions\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\",\"name\":\"Glossary\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/author\/adminglossary\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Leigh syndrome - Definition of Leigh syndrome","description":"Leigh Syndrome, also termed subacute necrotizing encephalomyelopathy, presents as a progressive neurometabolic disorder and often results from mitochondrial DNA mutation. Such mutations disrupt the mitochondria\u2019s ability to produce the cellular energy. Furthermore, the central nervous system appears to be most directly affected by mitochondrial dysfunction. The onset of Leigh syndrome is usually prior to 2 years of age, and although onset in adolescence and early adulthood is possible, it is rare (National Institute of Neurological Disorders and Stroke [NINDS], 2001).","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/","og_locale":"en_US","og_type":"article","og_title":"Leigh syndrome - Definition of Leigh syndrome","og_description":"Leigh Syndrome, also termed subacute necrotizing encephalomyelopathy, presents as a progressive neurometabolic disorder and often results from mitochondrial DNA mutation. Such mutations disrupt the mitochondria\u2019s ability to produce the cellular energy. Furthermore, the central nervous system appears to be most directly affected by mitochondrial dysfunction. The onset of Leigh syndrome is usually prior to 2 years of age, and although onset in adolescence and early adulthood is possible, it is rare (National Institute of Neurological Disorders and Stroke [NINDS], 2001).","og_url":"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/","og_site_name":"Glossary","article_published_time":"2021-05-27T10:46:29+00:00","author":"Glossary","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Glossary","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/","url":"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/","name":"Leigh syndrome - Definition of Leigh syndrome","isPartOf":{"@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/#website"},"datePublished":"2021-05-27T10:46:29+00:00","dateModified":"2021-05-27T10:46:29+00:00","author":{"@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5"},"description":"Leigh Syndrome, also termed subacute necrotizing encephalomyelopathy, presents as a progressive neurometabolic disorder and often results from mitochondrial DNA mutation. Such mutations disrupt the mitochondria\u2019s ability to produce the cellular energy. Furthermore, the central nervous system appears to be most directly affected by mitochondrial dysfunction. The onset of Leigh syndrome is usually prior to 2 years of age, and although onset in adolescence and early adulthood is possible, it is rare (National Institute of Neurological Disorders and Stroke [NINDS], 2001).","breadcrumb":{"@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/leigh-syndrome\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.healthbenefitstimes.com\/glossary\/"},{"@type":"ListItem","position":2,"name":"Leigh syndrome"}]},{"@type":"WebSite","@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/#website","url":"https:\/\/www.healthbenefitstimes.com\/glossary\/","name":"Glossary","description":"Difinitions","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.healthbenefitstimes.com\/glossary\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5","name":"Glossary","url":"https:\/\/www.healthbenefitstimes.com\/glossary\/author\/adminglossary\/"}]}},"_links":{"self":[{"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/posts\/108901","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/comments?post=108901"}],"version-history":[{"count":1,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/posts\/108901\/revisions"}],"predecessor-version":[{"id":108902,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/posts\/108901\/revisions\/108902"}],"wp:attachment":[{"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/media?parent=108901"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/categories?post=108901"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/tags?post=108901"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}