{"id":128038,"date":"2021-09-08T08:28:04","date_gmt":"2021-09-08T08:28:04","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=128038"},"modified":"2023-09-14T08:54:01","modified_gmt":"2023-09-14T08:54:01","slug":"cushing-syndrome","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/cushing-syndrome\/","title":{"rendered":"Cushing syndrome"},"content":{"rendered":"<p>A rare hormonal disorder produced by chronically increased levels of the hormone cortisol in the bloodstream; also known as hypercortisolism. Cushing syndrome tends to affect adults between the ages of 20 and 50 years.<\/p>\n<hr \/>\n<p>The condition resulting from excess amounts of corticosteroid hormones in the body. Symptoms include weight gain, reddening of the face and neck, excess growth of body and facial hair, raised blood pressure, loss of mineral from the bones (osteoporosis), raised blood glucose levels, and sometimes mental disturbances. The syndrome may be due to overstimulation of the adrenal glands by excessive amounts of the hormone ACTH, secreted either by a tumor of the pituitary gland (Cushing&#8217;s disease) or by a malignant tumor in the lung or elsewhere. Other causes include a benign or malignant tumor of the adrenal gland(s) resulting in excess activity of the gland and prolonged therapy with high doses of corticosteroid drugs (such as prednisone).<\/p>\n<hr \/>\n<p>Described in 1932 by Harvey Cushing, an American neurosurgeon, Cushing\u2019s syndrome is due to an excess production of cortisol. It can thus result from an adrenal tumour secreting cortisol, or from a pituitary gland tumour secreting ACTH and stimulating both adrenal cortexes to hypertrophy and secrete excess cortisol. It is sometimes the result of ectopic production of ACTH from non-endocrine tumours in the lung and pancreas.<\/p>\n<hr \/>\n<div class=\"group w-full text-token-text-primary border-b border-black\/10 dark:border-gray-900\/50 bg-gray-50 dark:bg-[#444654] sm:AIPRM__conversation__response\" data-testid=\"conversation-turn-25\">\n<div class=\"p-4 justify-center text-base md:gap-6 md:py-6 m-auto\">\n<div class=\"flex flex-1 gap-4 text-base mx-auto md:gap-6 md:max-w-2xl lg:max-w-[38rem] xl:max-w-3xl }\">\n<div class=\"relative flex w-[calc(100%-50px)] flex-col gap-1 md:gap-3 lg:w-[calc(100%-115px)]\">\n<div class=\"flex flex-grow flex-col gap-3 max-w-full\">\n<div class=\"min-h-[20px] flex flex-col items-start gap-3 overflow-x-auto whitespace-pre-wrap break-words\">\n<div class=\"markdown prose w-full break-words dark:prose-invert light AIPRM__conversation__response\">\n<p>A condition resulting from a disruption in the pituitary gland, marked by facial and trunk obesity, muscle weakness, elevated blood pressure, diabetes, infrequent or absent menstrual cycles, and various other abnormalities.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A rare hormonal disorder produced by chronically increased levels of the hormone cortisol in the bloodstream; also known as hypercortisolism. Cushing syndrome tends to affect adults between the ages of 20 and 50 years. The condition resulting from excess amounts of corticosteroid hormones in the body. Symptoms include weight gain, reddening of the face and [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-128038","post","type-post","status-publish","format-standard","hentry","category-c"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cushing syndrome - Definition of Cushing syndrome<\/title>\n<meta name=\"description\" content=\"A rare hormonal disorder produced by chronically increased levels of the hormone cortisol in the bloodstream; also known as hypercortisolism. Cushing syndrome tends to affect adults between the ages of 20 and 50 years.The condition resulting from excess amounts of corticosteroid hormones in the body. Symptoms include weight gain, reddening of the face and neck, excess growth of body and facial hair, raised blood pressure, loss of mineral from the bones (osteoporosis), raised blood glucose levels, and sometimes mental disturbances. The syndrome may be due to overstimulation of the adrenal glands by excessive amounts of the hormone ACTH, secreted either by a tumor of the pituitary gland (Cushing&#039;s disease) or by a malignant tumor in the lung or elsewhere. Other causes include a benign or malignant tumor of the adrenal gland(s) resulting in excess activity of the gland and prolonged therapy with high doses of corticosteroid drugs (such as prednisone).Described in 1932 by Harvey Cushing, an American neurosurgeon, Cushing\u2019s syndrome is due to an excess production of cortisol. It can thus result from an adrenal tumour secreting cortisol, or from a pituitary gland tumour secreting ACTH and stimulating both adrenal cortexes to hypertrophy and secrete excess cortisol. It is sometimes the result of ectopic production of ACTH from non-endocrine tumours in the lung and pancreas.A condition resulting from a disruption in the pituitary gland, marked by facial and trunk obesity, muscle weakness, elevated blood pressure, diabetes, infrequent or absent menstrual cycles, and various other abnormalities.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/cushing-syndrome\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cushing syndrome - Definition of Cushing syndrome\" \/>\n<meta property=\"og:description\" content=\"A rare hormonal disorder produced by chronically increased levels of the hormone cortisol in the bloodstream; also known as hypercortisolism. Cushing syndrome tends to affect adults between the ages of 20 and 50 years.The condition resulting from excess amounts of corticosteroid hormones in the body. Symptoms include weight gain, reddening of the face and neck, excess growth of body and facial hair, raised blood pressure, loss of mineral from the bones (osteoporosis), raised blood glucose levels, and sometimes mental disturbances. The syndrome may be due to overstimulation of the adrenal glands by excessive amounts of the hormone ACTH, secreted either by a tumor of the pituitary gland (Cushing&#039;s disease) or by a malignant tumor in the lung or elsewhere. Other causes include a benign or malignant tumor of the adrenal gland(s) resulting in excess activity of the gland and prolonged therapy with high doses of corticosteroid drugs (such as prednisone).Described in 1932 by Harvey Cushing, an American neurosurgeon, Cushing\u2019s syndrome is due to an excess production of cortisol. It can thus result from an adrenal tumour secreting cortisol, or from a pituitary gland tumour secreting ACTH and stimulating both adrenal cortexes to hypertrophy and secrete excess cortisol. It is sometimes the result of ectopic production of ACTH from non-endocrine tumours in the lung and pancreas.A condition resulting from a disruption in the pituitary gland, marked by facial and trunk obesity, muscle weakness, elevated blood pressure, diabetes, infrequent or absent menstrual cycles, and various other abnormalities.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.healthbenefitstimes.com\/glossary\/cushing-syndrome\/\" \/>\n<meta property=\"og:site_name\" content=\"Glossary\" \/>\n<meta property=\"article:published_time\" content=\"2021-09-08T08:28:04+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-09-14T08:54:01+00:00\" \/>\n<meta name=\"author\" content=\"Glossary\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Glossary\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/cushing-syndrome\/\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/cushing-syndrome\/\",\"name\":\"Cushing syndrome - Definition of Cushing syndrome\",\"isPartOf\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\"},\"datePublished\":\"2021-09-08T08:28:04+00:00\",\"dateModified\":\"2023-09-14T08:54:01+00:00\",\"author\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\"},\"description\":\"A rare hormonal disorder produced by chronically increased levels of the hormone cortisol in the bloodstream; also known as hypercortisolism. Cushing syndrome tends to affect adults between the ages of 20 and 50 years.The condition resulting from excess amounts of corticosteroid hormones in the body. Symptoms include weight gain, reddening of the face and neck, excess growth of body and facial hair, raised blood pressure, loss of mineral from the bones (osteoporosis), raised blood glucose levels, and sometimes mental disturbances. The syndrome may be due to overstimulation of the adrenal glands by excessive amounts of the hormone ACTH, secreted either by a tumor of the pituitary gland (Cushing's disease) or by a malignant tumor in the lung or elsewhere. Other causes include a benign or malignant tumor of the adrenal gland(s) resulting in excess activity of the gland and prolonged therapy with high doses of corticosteroid drugs (such as prednisone).Described in 1932 by Harvey Cushing, an American neurosurgeon, Cushing\u2019s syndrome is due to an excess production of cortisol. It can thus result from an adrenal tumour secreting cortisol, or from a pituitary gland tumour secreting ACTH and stimulating both adrenal cortexes to hypertrophy and secrete excess cortisol. It is sometimes the result of ectopic production of ACTH from non-endocrine tumours in the lung and pancreas.A condition resulting from a disruption in the pituitary gland, marked by facial and trunk obesity, muscle weakness, elevated blood pressure, diabetes, infrequent or absent menstrual cycles, and various other abnormalities.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/cushing-syndrome\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.healthbenefitstimes.com\/glossary\/cushing-syndrome\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/cushing-syndrome\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cushing syndrome\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/\",\"name\":\"Glossary\",\"description\":\"Difinitions\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\",\"name\":\"Glossary\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/author\/adminglossary\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Cushing syndrome - Definition of Cushing syndrome","description":"A rare hormonal disorder produced by chronically increased levels of the hormone cortisol in the bloodstream; also known as hypercortisolism. 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