{"id":129721,"date":"2021-09-17T08:24:06","date_gmt":"2021-09-17T08:24:06","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=129721"},"modified":"2023-10-04T07:35:10","modified_gmt":"2023-10-04T07:35:10","slug":"pemphigus-vulgaris","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/pemphigus-vulgaris\/","title":{"rendered":"Pemphigus vulgaris"},"content":{"rendered":"<p>A blistering disease caused by an autoimmune reaction toward proteins in the skin. Typically, men or women between 40 and 60 years old are affected. Painful and itchy blisters and sores may cover a significant portion of the body. Blisters may first appear in the mouth. Diagnosis is made through biopsy and blood tests. Treatment is with oral corticosteroids and drugs that suppress the immune system. Pemphigus vulgaris can lead to a life-threatening skin infection and is fatal if untreated.<\/p>\n<hr \/>\n<p>The most common form of pemphigus. Blisters develop suddenly and are round or oval, thin walled, tense, and translucent and bilateral in distribution. The lesions have little tendency to heal, and bleed easily when they burst. Since the introduction of corticosteroids, the prognosis for this autoimmune disease is favorable, but the mortality rate is still 5% to 15%. Immunosuppressive agents (e.g., azathioprine or cyclophosphamide) are used with corticosteroid therapy.<\/p>\n<hr \/>\n<p>Persistent pemphigus. In this variety, blistering sores develop on both the mucous membranes and the skin, and it can be life-threatening when left untreated.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A blistering disease caused by an autoimmune reaction toward proteins in the skin. Typically, men or women between 40 and 60 years old are affected. Painful and itchy blisters and sores may cover a significant portion of the body. Blisters may first appear in the mouth. Diagnosis is made through biopsy and blood tests. Treatment [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-129721","post","type-post","status-publish","format-standard","hentry","category-p"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pemphigus vulgaris - Definition of Pemphigus vulgaris<\/title>\n<meta name=\"description\" content=\"A blistering disease caused by an autoimmune reaction toward proteins in the skin. Typically, men or women between 40 and 60 years old are affected. Painful and itchy blisters and sores may cover a significant portion of the body. Blisters may first appear in the mouth. Diagnosis is made through biopsy and blood tests. Treatment is with oral corticosteroids and drugs that suppress the immune system. Pemphigus vulgaris can lead to a life-threatening skin infection and is fatal if untreated.The most common form of pemphigus. Blisters develop suddenly and are round or oval, thin walled, tense, and translucent and bilateral in distribution. The lesions have little tendency to heal, and bleed easily when they burst. Since the introduction of corticosteroids, the prognosis for this autoimmune disease is favorable, but the mortality rate is still 5% to 15%. Immunosuppressive agents (e.g., azathioprine or cyclophosphamide) are used with corticosteroid therapy.Persistent pemphigus. In this variety, blistering sores develop on both the mucous membranes and the skin, and it can be life-threatening when left untreated.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/pemphigus-vulgaris\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pemphigus vulgaris - Definition of Pemphigus vulgaris\" \/>\n<meta property=\"og:description\" content=\"A blistering disease caused by an autoimmune reaction toward proteins in the skin. Typically, men or women between 40 and 60 years old are affected. Painful and itchy blisters and sores may cover a significant portion of the body. Blisters may first appear in the mouth. Diagnosis is made through biopsy and blood tests. Treatment is with oral corticosteroids and drugs that suppress the immune system. Pemphigus vulgaris can lead to a life-threatening skin infection and is fatal if untreated.The most common form of pemphigus. Blisters develop suddenly and are round or oval, thin walled, tense, and translucent and bilateral in distribution. The lesions have little tendency to heal, and bleed easily when they burst. Since the introduction of corticosteroids, the prognosis for this autoimmune disease is favorable, but the mortality rate is still 5% to 15%. Immunosuppressive agents (e.g., azathioprine or cyclophosphamide) are used with corticosteroid therapy.Persistent pemphigus. In this variety, blistering sores develop on both the mucous membranes and the skin, and it can be life-threatening when left untreated.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.healthbenefitstimes.com\/glossary\/pemphigus-vulgaris\/\" \/>\n<meta property=\"og:site_name\" content=\"Glossary\" \/>\n<meta property=\"article:published_time\" content=\"2021-09-17T08:24:06+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-10-04T07:35:10+00:00\" \/>\n<meta name=\"author\" content=\"Glossary\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Glossary\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/pemphigus-vulgaris\/\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/pemphigus-vulgaris\/\",\"name\":\"Pemphigus vulgaris - Definition of Pemphigus vulgaris\",\"isPartOf\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\"},\"datePublished\":\"2021-09-17T08:24:06+00:00\",\"dateModified\":\"2023-10-04T07:35:10+00:00\",\"author\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\"},\"description\":\"A blistering disease caused by an autoimmune reaction toward proteins in the skin. 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