Paget\u2019s Disease of Bone, or osteitis deformans, is a chronic disease in which the bones especially those of the skull, limbs, and spine gradually become thick and also soft, causing them to bend. It is said to be the most common form of bone disease in the world, and an estimated 600,000 people in England may suffer from it. The condition seldom occurs under the age of 40. Pain is its most unpleasant manifestation and it may lead to arthritis, bowing of the legs, enlargement of the skull and headache. The cause is not known, and there is no known cure, but satisfactory results are being obtained from the use of calcitonin and a group of drugs known as bisphosphonates (e.g. etidronate). Those with the disease can obtain help and advice from the National Association for the Relief of Paget\u2019s Disease.<\/p>\n
Paget’s disease is a chronic condition, the etiology of which remains unknown. It predominantly affects individuals in middle age and the elderly, manifesting as the enlargement and deformation of bones. This disorder is characterized by an abnormal and excessive turnover of bone tissue, leading to weakened bones, which can give rise to symptoms such as bone pain, arthritis, deformities, and fractures.<\/p>\n
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Paget\u2019s Disease of Bone, or osteitis deformans, is a chronic disease in which the bones especially those of the skull, limbs, and spine gradually become thick and also soft, causing them to bend. It is said to be the most common form of bone disease in the world, and an estimated 600,000 people in England […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-149404","post","type-post","status-publish","format-standard","hentry","category-p"],"yoast_head":"\n