{"id":156320,"date":"2022-05-02T06:41:21","date_gmt":"2022-05-02T06:41:21","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=156320"},"modified":"2022-05-02T06:41:21","modified_gmt":"2022-05-02T06:41:21","slug":"cold-autoagglutinin","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/cold-autoagglutinin\/","title":{"rendered":"Cold autoagglutinin"},"content":{"rendered":"<p>An IgM class autoantibody that is activated only when the temperature falls below 100\u00b0C. These antibodies may destroy the patient&#8217;s red blood cells and are one cause of autoimmune\u00a0hemolytic anemia. They are found in the serum of patients (esp. those older than 50 years) with atypical (e.g., mycoplasma) pneumonia, infectious mononucleosis, cytomegalovirus infections, mumps, and certain blood diseases. The complement-mediated, autoimmune hemolysis that results is an example of a type II hypersensitivity reaction.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An IgM class autoantibody that is activated only when the temperature falls below 100\u00b0C. These antibodies may destroy the patient&#8217;s red blood cells and are one cause of autoimmune\u00a0hemolytic anemia. They are found in the serum of patients (esp. those older than 50 years) with atypical (e.g., mycoplasma) pneumonia, infectious mononucleosis, cytomegalovirus infections, mumps, and [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-156320","post","type-post","status-publish","format-standard","hentry","category-c"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cold autoagglutinin - Definition of Cold autoagglutinin<\/title>\n<meta name=\"description\" content=\"An IgM class autoantibody that is activated only when the temperature falls below 100\u00b0C. These antibodies may destroy the patient&#039;s red blood cells and are one cause of autoimmune\u00a0hemolytic anemia. They are found in the serum of patients (esp. those older than 50 years) with atypical (e.g., mycoplasma) pneumonia, infectious mononucleosis, cytomegalovirus infections, mumps, and certain blood diseases. The complement-mediated, autoimmune hemolysis that results is an example of a type II hypersensitivity reaction.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/cold-autoagglutinin\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cold autoagglutinin - Definition of Cold autoagglutinin\" \/>\n<meta property=\"og:description\" content=\"An IgM class autoantibody that is activated only when the temperature falls below 100\u00b0C. These antibodies may destroy the patient&#039;s red blood cells and are one cause of autoimmune\u00a0hemolytic anemia. They are found in the serum of patients (esp. those older than 50 years) with atypical (e.g., mycoplasma) pneumonia, infectious mononucleosis, cytomegalovirus infections, mumps, and certain blood diseases. 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