{"id":161240,"date":"2022-05-26T08:10:14","date_gmt":"2022-05-26T08:10:14","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=161240"},"modified":"2023-08-18T05:55:49","modified_gmt":"2023-08-18T05:55:49","slug":"philadelphia-chromosomes","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/","title":{"rendered":"Philadelphia chromosomes"},"content":{"rendered":"<p>An abnormal chromosome 22 in which there is translocation of the distal portion of its long arm to chromosome 9. It is found in leukocyte cultures of many patients with chronic myelocytic leukemia. The Philadelphia chromosome was the first chromosomal change found to be characteristic of a human disease.<\/p>\n<hr \/>\n<div class=\"group w-full text-gray-800 dark:text-gray-100 border-b border-black\/10 dark:border-gray-900\/50 bg-gray-50 dark:bg-[#444654] sm:AIPRM__conversation__response\">\n<div class=\"flex p-4 gap-4 text-base md:gap-6 md:max-w-2xl lg:max-w-[38rem] xl:max-w-3xl md:py-6 lg:px-0 m-auto\">\n<div class=\"relative flex w-[calc(100%-50px)] flex-col gap-1 md:gap-3 lg:w-[calc(100%-115px)]\">\n<div class=\"flex flex-grow flex-col gap-3\">\n<div class=\"min-h-[20px] flex flex-col items-start gap-4 whitespace-pre-wrap break-words\">\n<div class=\"markdown prose w-full break-words dark:prose-invert light AIPRM__conversation__response\">\n<p>An atypical chromosome observed in individuals affected by a chronic type of leukemia, distinct from those with polycythemia vera (PV).<\/p>\n<hr \/>\n<p>A genetic irregularity linked to a particular variant of leukemia. In this anomaly, a segment of one copy of chromosome 22 is absent; this section becomes detached and subsequently reattaches to a copy of chromosome 9.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>An abnormal chromosome 22 in which there is translocation of the distal portion of its long arm to chromosome 9. It is found in leukocyte cultures of many patients with chronic myelocytic leukemia. The Philadelphia chromosome was the first chromosomal change found to be characteristic of a human disease. An atypical chromosome observed in individuals [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-161240","post","type-post","status-publish","format-standard","hentry","category-p"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Philadelphia chromosomes - Definition of Philadelphia chromosomes<\/title>\n<meta name=\"description\" content=\"An abnormal chromosome 22 in which there is translocation of the distal portion of its long arm to chromosome 9. It is found in leukocyte cultures of many patients with chronic myelocytic leukemia. The Philadelphia chromosome was the first chromosomal change found to be characteristic of a human disease.An atypical chromosome observed in individuals affected by a chronic type of leukemia, distinct from those with polycythemia vera (PV).A genetic irregularity linked to a particular variant of leukemia. In this anomaly, a segment of one copy of chromosome 22 is absent; this section becomes detached and subsequently reattaches to a copy of chromosome 9.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Philadelphia chromosomes - Definition of Philadelphia chromosomes\" \/>\n<meta property=\"og:description\" content=\"An abnormal chromosome 22 in which there is translocation of the distal portion of its long arm to chromosome 9. It is found in leukocyte cultures of many patients with chronic myelocytic leukemia. The Philadelphia chromosome was the first chromosomal change found to be characteristic of a human disease.An atypical chromosome observed in individuals affected by a chronic type of leukemia, distinct from those with polycythemia vera (PV).A genetic irregularity linked to a particular variant of leukemia. In this anomaly, a segment of one copy of chromosome 22 is absent; this section becomes detached and subsequently reattaches to a copy of chromosome 9.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/\" \/>\n<meta property=\"og:site_name\" content=\"Glossary\" \/>\n<meta property=\"article:published_time\" content=\"2022-05-26T08:10:14+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-08-18T05:55:49+00:00\" \/>\n<meta name=\"author\" content=\"Glossary\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Glossary\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/\",\"name\":\"Philadelphia chromosomes - Definition of Philadelphia chromosomes\",\"isPartOf\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\"},\"datePublished\":\"2022-05-26T08:10:14+00:00\",\"dateModified\":\"2023-08-18T05:55:49+00:00\",\"author\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\"},\"description\":\"An abnormal chromosome 22 in which there is translocation of the distal portion of its long arm to chromosome 9. It is found in leukocyte cultures of many patients with chronic myelocytic leukemia. The Philadelphia chromosome was the first chromosomal change found to be characteristic of a human disease.An atypical chromosome observed in individuals affected by a chronic type of leukemia, distinct from those with polycythemia vera (PV).A genetic irregularity linked to a particular variant of leukemia. In this anomaly, a segment of one copy of chromosome 22 is absent; this section becomes detached and subsequently reattaches to a copy of chromosome 9.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Philadelphia chromosomes\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/\",\"name\":\"Glossary\",\"description\":\"Difinitions\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\",\"name\":\"Glossary\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/author\/adminglossary\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Philadelphia chromosomes - Definition of Philadelphia chromosomes","description":"An abnormal chromosome 22 in which there is translocation of the distal portion of its long arm to chromosome 9. It is found in leukocyte cultures of many patients with chronic myelocytic leukemia. The Philadelphia chromosome was the first chromosomal change found to be characteristic of a human disease.An atypical chromosome observed in individuals affected by a chronic type of leukemia, distinct from those with polycythemia vera (PV).A genetic irregularity linked to a particular variant of leukemia. In this anomaly, a segment of one copy of chromosome 22 is absent; this section becomes detached and subsequently reattaches to a copy of chromosome 9.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/","og_locale":"en_US","og_type":"article","og_title":"Philadelphia chromosomes - Definition of Philadelphia chromosomes","og_description":"An abnormal chromosome 22 in which there is translocation of the distal portion of its long arm to chromosome 9. It is found in leukocyte cultures of many patients with chronic myelocytic leukemia. The Philadelphia chromosome was the first chromosomal change found to be characteristic of a human disease.An atypical chromosome observed in individuals affected by a chronic type of leukemia, distinct from those with polycythemia vera (PV).A genetic irregularity linked to a particular variant of leukemia. In this anomaly, a segment of one copy of chromosome 22 is absent; this section becomes detached and subsequently reattaches to a copy of chromosome 9.","og_url":"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/","og_site_name":"Glossary","article_published_time":"2022-05-26T08:10:14+00:00","article_modified_time":"2023-08-18T05:55:49+00:00","author":"Glossary","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Glossary","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/","url":"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/","name":"Philadelphia chromosomes - Definition of Philadelphia chromosomes","isPartOf":{"@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/#website"},"datePublished":"2022-05-26T08:10:14+00:00","dateModified":"2023-08-18T05:55:49+00:00","author":{"@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5"},"description":"An abnormal chromosome 22 in which there is translocation of the distal portion of its long arm to chromosome 9. It is found in leukocyte cultures of many patients with chronic myelocytic leukemia. The Philadelphia chromosome was the first chromosomal change found to be characteristic of a human disease.An atypical chromosome observed in individuals affected by a chronic type of leukemia, distinct from those with polycythemia vera (PV).A genetic irregularity linked to a particular variant of leukemia. In this anomaly, a segment of one copy of chromosome 22 is absent; this section becomes detached and subsequently reattaches to a copy of chromosome 9.","breadcrumb":{"@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/philadelphia-chromosomes\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.healthbenefitstimes.com\/glossary\/"},{"@type":"ListItem","position":2,"name":"Philadelphia chromosomes"}]},{"@type":"WebSite","@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/#website","url":"https:\/\/www.healthbenefitstimes.com\/glossary\/","name":"Glossary","description":"Difinitions","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.healthbenefitstimes.com\/glossary\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5","name":"Glossary","url":"https:\/\/www.healthbenefitstimes.com\/glossary\/author\/adminglossary\/"}]}},"_links":{"self":[{"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/posts\/161240","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/comments?post=161240"}],"version-history":[{"count":3,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/posts\/161240\/revisions"}],"predecessor-version":[{"id":237862,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/posts\/161240\/revisions\/237862"}],"wp:attachment":[{"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/media?parent=161240"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/categories?post=161240"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthbenefitstimes.com\/glossary\/wp-json\/wp\/v2\/tags?post=161240"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}