{"id":168716,"date":"2022-07-04T06:20:36","date_gmt":"2022-07-04T06:20:36","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=168716"},"modified":"2022-07-04T06:20:36","modified_gmt":"2022-07-04T06:20:36","slug":"endothelium-derived-relaxing-factor","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/endothelium-derived-relaxing-factor\/","title":{"rendered":"Endothelium-derived relaxing factor"},"content":{"rendered":"<p>An active vasodilator released by the vascular endothelium. It facilitates relaxation of vascular smooth muscle and inhibition of adhesion and aggregation of platelets. When the normal function of the endothelium is disrupted by mechanical trauma, hypertension, hypercholesterolemia, or atherosclerosis, less EDRF is released and the inhibition of platelet aggregation is decreased. In addition, the damaged vessels constrict. This favors the formation of thrombi.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An active vasodilator released by the vascular endothelium. It facilitates relaxation of vascular smooth muscle and inhibition of adhesion and aggregation of platelets. When the normal function of the endothelium is disrupted by mechanical trauma, hypertension, hypercholesterolemia, or atherosclerosis, less EDRF is released and the inhibition of platelet aggregation is decreased. In addition, the damaged [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-168716","post","type-post","status-publish","format-standard","hentry","category-e"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Endothelium-derived relaxing factor - Definition of Endothelium-derived relaxing factor<\/title>\n<meta name=\"description\" content=\"An active vasodilator released by the vascular endothelium. It facilitates relaxation of vascular smooth muscle and inhibition of adhesion and aggregation of platelets. When the normal function of the endothelium is disrupted by mechanical trauma, hypertension, hypercholesterolemia, or atherosclerosis, less EDRF is released and the inhibition of platelet aggregation is decreased. In addition, the damaged vessels constrict. This favors the formation of thrombi.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/endothelium-derived-relaxing-factor\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Endothelium-derived relaxing factor - Definition of Endothelium-derived relaxing factor\" \/>\n<meta property=\"og:description\" content=\"An active vasodilator released by the vascular endothelium. It facilitates relaxation of vascular smooth muscle and inhibition of adhesion and aggregation of platelets. When the normal function of the endothelium is disrupted by mechanical trauma, hypertension, hypercholesterolemia, or atherosclerosis, less EDRF is released and the inhibition of platelet aggregation is decreased. 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