{"id":172550,"date":"2022-07-24T06:43:38","date_gmt":"2022-07-24T06:43:38","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=172550"},"modified":"2022-07-24T06:43:38","modified_gmt":"2022-07-24T06:43:38","slug":"anion-gap","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/anion-gap\/","title":{"rendered":"Anion gap"},"content":{"rendered":"<p>The difference between the measured cations sodium (Na+) and potassium (K+) and the measured anions chloride (CP) and bicarbonate (HC03_). In accordance with the principle of electroneutrality, in any body fluid the number of net positive charges contributed by cations must equal the number of net negative charges contributed by anions. The apparent difference is accounted for by the unmeasured anions present (the anion gap); these include lactate, sulfates, phosphates, proteins, ketones, and other organic acids. In general, an anion gap of 8 to 18 mmol\/L is normal. An increased value is present in some forms of metabolic acidosis.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The difference between the measured cations sodium (Na+) and potassium (K+) and the measured anions chloride (CP) and bicarbonate (HC03_). In accordance with the principle of electroneutrality, in any body fluid the number of net positive charges contributed by cations must equal the number of net negative charges contributed by anions. The apparent difference is [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-172550","post","type-post","status-publish","format-standard","hentry","category-a"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Anion gap - Definition of Anion gap<\/title>\n<meta name=\"description\" content=\"The difference between the measured cations sodium (Na+) and potassium (K+) and the measured anions chloride (CP) and bicarbonate (HC03_). In accordance with the principle of electroneutrality, in any body fluid the number of net positive charges contributed by cations must equal the number of net negative charges contributed by anions. The apparent difference is accounted for by the unmeasured anions present (the anion gap); these include lactate, sulfates, phosphates, proteins, ketones, and other organic acids. In general, an anion gap of 8 to 18 mmol\/L is normal. An increased value is present in some forms of metabolic acidosis.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/anion-gap\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Anion gap - Definition of Anion gap\" \/>\n<meta property=\"og:description\" content=\"The difference between the measured cations sodium (Na+) and potassium (K+) and the measured anions chloride (CP) and bicarbonate (HC03_). In accordance with the principle of electroneutrality, in any body fluid the number of net positive charges contributed by cations must equal the number of net negative charges contributed by anions. The apparent difference is accounted for by the unmeasured anions present (the anion gap); these include lactate, sulfates, phosphates, proteins, ketones, and other organic acids. In general, an anion gap of 8 to 18 mmol\/L is normal. An increased value is present in some forms of metabolic acidosis.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.healthbenefitstimes.com\/glossary\/anion-gap\/\" \/>\n<meta property=\"og:site_name\" content=\"Glossary\" \/>\n<meta property=\"article:published_time\" content=\"2022-07-24T06:43:38+00:00\" \/>\n<meta name=\"author\" content=\"Glossary\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Glossary\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/anion-gap\/\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/anion-gap\/\",\"name\":\"Anion gap - Definition of Anion gap\",\"isPartOf\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\"},\"datePublished\":\"2022-07-24T06:43:38+00:00\",\"dateModified\":\"2022-07-24T06:43:38+00:00\",\"author\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\"},\"description\":\"The difference between the measured cations sodium (Na+) and potassium (K+) and the measured anions chloride (CP) and bicarbonate (HC03_). 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