{"id":184492,"date":"2022-09-21T05:22:49","date_gmt":"2022-09-21T05:22:49","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=184492"},"modified":"2022-09-21T05:22:49","modified_gmt":"2022-09-21T05:22:49","slug":"mixed-lymphocyte-culture-reaction","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/mixed-lymphocyte-culture-reaction\/","title":{"rendered":"Mixed lymphocyte culture reaction"},"content":{"rendered":"<p>A laboratory test in which lymphocytes from different individuals are mixed to identify the presence of particular HLA class II antigens. The T cells from the \u201cresponder\u201d will synthesize DNA and proliferate only if they do not have the same histocompatibility antigens as the \u201cdonor cells,\u201d homozygous cells with known HLA types. The donor cells are irradiated to prevent their proliferation during the test.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A laboratory test in which lymphocytes from different individuals are mixed to identify the presence of particular HLA class II antigens. The T cells from the \u201cresponder\u201d will synthesize DNA and proliferate only if they do not have the same histocompatibility antigens as the \u201cdonor cells,\u201d homozygous cells with known HLA types. The donor cells [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-184492","post","type-post","status-publish","format-standard","hentry","category-m"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mixed lymphocyte culture reaction - Definition of Mixed lymphocyte culture reaction<\/title>\n<meta name=\"description\" content=\"A laboratory test in which lymphocytes from different individuals are mixed to identify the presence of particular HLA class II antigens. The T cells from the \u201cresponder\u201d will synthesize DNA and proliferate only if they do not have the same histocompatibility antigens as the \u201cdonor cells,\u201d homozygous cells with known HLA types. 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