{"id":21923,"date":"2020-06-23T07:11:57","date_gmt":"2020-06-23T07:11:57","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=21923"},"modified":"2023-03-17T06:37:12","modified_gmt":"2023-03-17T06:37:12","slug":"drug-tolerance","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/drug-tolerance\/","title":{"rendered":"Drug Tolerance"},"content":{"rendered":"

\"\"<\/a>Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from drug resistance where in an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from maximum tolerated dose and no-observed-adverse-effect level.<\/p>\n

\n

Repeated use of some substance or drug, often narcotics, so that larger and larger doses are required to produce the same physiologic and\/or psychological effect obtained previously by a smaller dose.<\/p>\n

\n

A condition in which greater and greater amounts of a drug are needed to be effective.<\/p>\n

\n

A condition in which a drug has been given to someone for so long that his or her body no longer reacts to it, and the dosage has to be increased.<\/p>\n

\n

The progressive decrease in the effectiveness of a drug.<\/p>\n

\n

A condition in which a user needs more of a drug to get the same effect.<\/p>\n

\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from drug resistance where in an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from maximum tolerated […]<\/p>\n","protected":false},"author":2,"featured_media":48260,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-21923","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-d"],"yoast_head":"\nDrug Tolerance - Definition of Drug Tolerance<\/title>\n<meta name=\"description\" content=\"Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from drug resistance where in an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. 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