{"id":22342,"date":"2020-06-24T05:59:45","date_gmt":"2020-06-24T05:59:45","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=22342"},"modified":"2022-08-12T07:11:26","modified_gmt":"2022-08-12T07:11:26","slug":"hybridomas","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/hybridomas\/","title":{"rendered":"Hybridomas"},"content":{"rendered":"<p>Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure or &#8220;monoclonal&#8221; antibodies or T-cell products, identical to those produced by the immunologically competent parent, and continually grow and divide as the neoplastic parent.<\/p>\n<hr \/>\n<p>The cell line produced by fusing a myeloma (tumor cell) with a lymphocyte (which makes antibodies); it continues indefinitely to express the immunoglobulins (antibodies) of both parent cells.<\/p>\n<hr \/>\n<p>A hybrid cell created by fusing a B lymphocyte with a long-lived neoplastic plasma cell, or a T lymphocyte with a lymphoma cell. A B-cell hybridoma secretes a single specific antibody.<\/p>\n<hr \/>\n<p>A cell produced by the fusion of a spleen cell from a mouse immunized with a specific antigen and a human multiple myeloma cell (a cancerous plasma B cell that makes antibodies). After the fusion, cells are screened to identify those capable of producing a continuous supply of monoclonal antibodies to the specific antigen.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure or &#8220;monoclonal&#8221; antibodies or T-cell products, identical to those produced by the immunologically competent parent, and continually grow and divide as the neoplastic parent. The cell line produced by fusing a myeloma (tumor cell) with [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-22342","post","type-post","status-publish","format-standard","hentry","category-h"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hybridomas - Definition of Hybridomas<\/title>\n<meta name=\"description\" content=\"Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure or &quot;monoclonal&quot; antibodies or T-cell products, identical to those produced by the immunologically competent parent, and continually grow and divide as the neoplastic parent.The cell line produced by fusing a myeloma (tumor cell) with a lymphocyte (which makes antibodies); it continues indefinitely to express the immunoglobulins (antibodies) of both parent cells.A hybrid cell created by fusing a B lymphocyte with a long-lived neoplastic plasma cell, or a T lymphocyte with a lymphoma cell. A B-cell hybridoma secretes a single specific antibody.A cell produced by the fusion of a spleen cell from a mouse immunized with a specific antigen and a human multiple myeloma cell (a cancerous plasma B cell that makes antibodies). After the fusion, cells are screened to identify those capable of producing a continuous supply of monoclonal antibodies to the specific antigen.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/hybridomas\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hybridomas - Definition of Hybridomas\" \/>\n<meta property=\"og:description\" content=\"Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure or &quot;monoclonal&quot; antibodies or T-cell products, identical to those produced by the immunologically competent parent, and continually grow and divide as the neoplastic parent.The cell line produced by fusing a myeloma (tumor cell) with a lymphocyte (which makes antibodies); it continues indefinitely to express the immunoglobulins (antibodies) of both parent cells.A hybrid cell created by fusing a B lymphocyte with a long-lived neoplastic plasma cell, or a T lymphocyte with a lymphoma cell. A B-cell hybridoma secretes a single specific antibody.A cell produced by the fusion of a spleen cell from a mouse immunized with a specific antigen and a human multiple myeloma cell (a cancerous plasma B cell that makes antibodies). 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