A protein expressed in many tissues and concentrated in the synapses of neurons. Although its primary function is not known, app is most commonly studied as the precursor molecule whose degradation generates the beta-amyloid that appears to be the main constituent of amyloid plaques in the brains of patients with alzheimer\u2019s disease.<\/p>\n
A (collective) set of protein molecules, from which are derived Amyloid \u03b2 Protein (A\u03b2P).<\/p>\n
A compound found in cell membranes from which beta amyloid is derived. A mutation of the gene causes early onset Alzheimer\u2019s disease in a few families.<\/p>\n
An integral membrane protein concentrated at neuron synapses that is cleaved biochemically into components, one of which is the Alzheimer\u2019s disease associated beta amyloid. Mutations in the gene for APP on chromosome 21 account for less than 5% of early-onset familial Alzheimer\u2019s disease.<\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
A protein expressed in many tissues and concentrated in the synapses of neurons. Although its primary function is not known, app is most commonly studied as the precursor molecule whose degradation generates the beta-amyloid that appears to be the main constituent of amyloid plaques in the brains of patients with alzheimer\u2019s disease. A (collective) set […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-25812","post","type-post","status-publish","format-standard","hentry","category-a"],"yoast_head":"\n