{"id":28356,"date":"2020-07-13T11:04:54","date_gmt":"2020-07-13T11:04:54","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=28356"},"modified":"2023-06-18T06:12:17","modified_gmt":"2023-06-18T06:12:17","slug":"neurofibrillary-tangles","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/neurofibrillary-tangles\/","title":{"rendered":"Neurofibrillary tangles"},"content":{"rendered":"<p>Nonsoluble twisted fibers found inside the brain\u2019s cells. These tangles consist primarily of a protein called TAU, which forms part of a structure called a microtubule. The microtubule helps transport nutrients and other important substances from one part of the nerve cell to another. In Alzheimer&#8217;s disease, however, the tau protein is abnormal and the microtubule structures collapse.<\/p>\n<hr \/>\n<p>Misshaped filaments on the surface of the brain associated with Alzheimer&#8217;s-type dementia.<\/p>\n<hr \/>\n<div class=\"group w-full text-gray-800 dark:text-gray-100 border-b border-black\/10 dark:border-gray-900\/50 bg-gray-50 dark:bg-[#444654] sm:AIPRM__conversation__response\">\n<div class=\"flex p-4 gap-4 text-base md:gap-6 md:max-w-2xl lg:max-w-[38rem] xl:max-w-3xl md:py-6 lg:px-0 m-auto\">\n<div class=\"relative flex w-[calc(100%-50px)] flex-col gap-1 md:gap-3 lg:w-[calc(100%-115px)]\">\n<div class=\"flex flex-grow flex-col gap-3\">\n<div class=\"min-h-[20px] flex flex-col items-start gap-4 whitespace-pre-wrap break-words\">\n<div class=\"markdown prose w-full break-words dark:prose-invert light AIPRM__conversation__response\">\n<p>Buildups of entangled protein fragments within brain nerve cells that serve as a diagnostic characteristic of Alzheimer&#8217;s disease.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Nonsoluble twisted fibers found inside the brain\u2019s cells. These tangles consist primarily of a protein called TAU, which forms part of a structure called a microtubule. The microtubule helps transport nutrients and other important substances from one part of the nerve cell to another. In Alzheimer&#8217;s disease, however, the tau protein is abnormal and the [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[],"class_list":["post-28356","post","type-post","status-publish","format-standard","hentry","category-n"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Neurofibrillary tangles - Definition of Neurofibrillary tangles<\/title>\n<meta name=\"description\" content=\"Nonsoluble twisted fibers found inside the brain\u2019s cells. These tangles consist primarily of a protein called TAU, which forms part of a structure called a microtubule. The microtubule helps transport nutrients and other important substances from one part of the nerve cell to another. In Alzheimer&#039;s disease, however, the tau protein is abnormal and the microtubule structures collapse.Misshaped filaments on the surface of the brain associated with Alzheimer&#039;s-type dementia.Buildups of entangled protein fragments within brain nerve cells that serve as a diagnostic characteristic of Alzheimer&#039;s disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/neurofibrillary-tangles\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Neurofibrillary tangles - Definition of Neurofibrillary tangles\" \/>\n<meta property=\"og:description\" content=\"Nonsoluble twisted fibers found inside the brain\u2019s cells. These tangles consist primarily of a protein called TAU, which forms part of a structure called a microtubule. The microtubule helps transport nutrients and other important substances from one part of the nerve cell to another. In Alzheimer&#039;s disease, however, the tau protein is abnormal and the microtubule structures collapse.Misshaped filaments on the surface of the brain associated with Alzheimer&#039;s-type dementia.Buildups of entangled protein fragments within brain nerve cells that serve as a diagnostic characteristic of Alzheimer&#039;s disease.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.healthbenefitstimes.com\/glossary\/neurofibrillary-tangles\/\" \/>\n<meta property=\"og:site_name\" content=\"Glossary\" \/>\n<meta property=\"article:published_time\" content=\"2020-07-13T11:04:54+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-06-18T06:12:17+00:00\" \/>\n<meta name=\"author\" content=\"Glossary\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Glossary\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/neurofibrillary-tangles\/\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/neurofibrillary-tangles\/\",\"name\":\"Neurofibrillary tangles - Definition of Neurofibrillary tangles\",\"isPartOf\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\"},\"datePublished\":\"2020-07-13T11:04:54+00:00\",\"dateModified\":\"2023-06-18T06:12:17+00:00\",\"author\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\"},\"description\":\"Nonsoluble twisted fibers found inside the brain\u2019s cells. These tangles consist primarily of a protein called TAU, which forms part of a structure called a microtubule. The microtubule helps transport nutrients and other important substances from one part of the nerve cell to another. 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