{"id":38110,"date":"2020-08-18T09:35:56","date_gmt":"2020-08-18T09:35:56","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=38110"},"modified":"2020-08-18T09:35:56","modified_gmt":"2020-08-18T09:35:56","slug":"heavy-chain-variable-vh-domains","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/heavy-chain-variable-vh-domains\/","title":{"rendered":"Heavy-chain variable (VH) domains"},"content":{"rendered":"

The regions (domains) of the antibody (molecule’s) “heavy chain” that vary in their amino acid sequence. The “chains” (of atoms) comprising the antibody (immunoglobulin) molecule consist of a region of variable (V) amino acid sequence and a region in which the amino acid sequence remains constant (C). An antibody molecule possesses two antigen binding sites, and it is the variable domains of the light (VL) and heavy (VH) chains which contribute to this (antigen binding ability).<\/p>\n

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The regions (domains) of the antibody (molecule’s) “heavy chain” that vary in their amino acid sequence. The “chains” (of atoms) comprising the antibody (immunoglobulin) molecule consist of a region of variable (V) amino acid sequence and a region in which the amino acid sequence remains constant (C). An antibody molecule possesses two antigen binding sites, […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-38110","post","type-post","status-publish","format-standard","hentry","category-h"],"yoast_head":"\nHeavy-chain variable (VH) domains - Definition of Heavy-chain variable (VH) domains<\/title>\n<meta name=\"description\" content=\"The regions (domains) of the antibody (molecule's) "heavy chain" that vary in their amino acid sequence. The "chains" (of atoms) comprising the antibody (immunoglobulin) molecule consist of a region of variable (V) amino acid sequence and a region in which the amino acid sequence remains constant (C). An antibody molecule possesses two antigen binding sites, and it is the variable domains of the light (VL) and heavy (VH) chains which contribute to this (antigen binding ability).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/heavy-chain-variable-vh-domains\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Heavy-chain variable (VH) domains - Definition of Heavy-chain variable (VH) domains\" \/>\n<meta property=\"og:description\" content=\"The regions (domains) of the antibody (molecule's) "heavy chain" that vary in their amino acid sequence. The "chains" (of atoms) comprising the antibody (immunoglobulin) molecule consist of a region of variable (V) amino acid sequence and a region in which the amino acid sequence remains constant (C). An antibody molecule possesses two antigen binding sites, and it is the variable domains of the light (VL) and heavy (VH) chains which contribute to this (antigen binding ability).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.healthbenefitstimes.com\/glossary\/heavy-chain-variable-vh-domains\/\" \/>\n<meta property=\"og:site_name\" content=\"Glossary\" \/>\n<meta property=\"article:published_time\" content=\"2020-08-18T09:35:56+00:00\" \/>\n<meta name=\"author\" content=\"Glossary\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Glossary\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/heavy-chain-variable-vh-domains\/\",\"url\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/heavy-chain-variable-vh-domains\/\",\"name\":\"Heavy-chain variable (VH) domains - Definition of Heavy-chain variable (VH) domains\",\"isPartOf\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#website\"},\"datePublished\":\"2020-08-18T09:35:56+00:00\",\"dateModified\":\"2020-08-18T09:35:56+00:00\",\"author\":{\"@id\":\"https:\/\/www.healthbenefitstimes.com\/glossary\/#\/schema\/person\/ccfef987a4882e6356ae6d77d33e74c5\"},\"description\":\"The regions (domains) of the antibody (molecule's) \\\"heavy chain\\\" that vary in their amino acid sequence. The \\\"chains\\\" (of atoms) comprising the antibody (immunoglobulin) molecule consist of a region of variable (V) amino acid sequence and a region in which the amino acid sequence remains constant (C). 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