{"id":38607,"date":"2020-09-06T10:46:15","date_gmt":"2020-09-06T10:46:15","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=38607"},"modified":"2020-09-06T10:46:15","modified_gmt":"2020-09-06T10:46:15","slug":"naked-gene","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/naked-gene\/","title":{"rendered":"Naked gene"},"content":{"rendered":"<p>A bare gene (strand of DNA) that has been extracted from or derived (e.g., synthesized from sequencing data) from a pathogen. During the 1990s, it was discovered that inserting such &#8220;naked&#8221; genes into certain tissues in the (usual disease host) organism would sometimes cause those tissues to take up the &#8220;naked&#8221; genes and express some of the cell-surface proteins indigenous to that pathogen. When that happens, and the (host&#8217;s) immune system mounts an immune response (to those cell-surface proteins, and thus to the pathogen), these &#8220;naked&#8221; genes are referred to as &#8220;DNA vaccines.&#8221;<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A bare gene (strand of DNA) that has been extracted from or derived (e.g., synthesized from sequencing data) from a pathogen. During the 1990s, it was discovered that inserting such &#8220;naked&#8221; genes into certain tissues in the (usual disease host) organism would sometimes cause those tissues to take up the &#8220;naked&#8221; genes and express some [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[],"class_list":["post-38607","post","type-post","status-publish","format-standard","hentry","category-n"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Naked gene - Definition of Naked gene<\/title>\n<meta name=\"description\" content=\"A bare gene (strand of DNA) that has been extracted from or derived (e.g., synthesized from sequencing data) from a pathogen. During the 1990s, it was discovered that inserting such &quot;naked&quot; genes into certain tissues in the (usual disease host) organism would sometimes cause those tissues to take up the &quot;naked&quot; genes and express some of the cell-surface proteins indigenous to that pathogen. When that happens, and the (host&#039;s) immune system mounts an immune response (to those cell-surface proteins, and thus to the pathogen), these &quot;naked&quot; genes are referred to as &quot;DNA vaccines.&quot;\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/naked-gene\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Naked gene - Definition of Naked gene\" \/>\n<meta property=\"og:description\" content=\"A bare gene (strand of DNA) that has been extracted from or derived (e.g., synthesized from sequencing data) from a pathogen. During the 1990s, it was discovered that inserting such &quot;naked&quot; genes into certain tissues in the (usual disease host) organism would sometimes cause those tissues to take up the &quot;naked&quot; genes and express some of the cell-surface proteins indigenous to that pathogen. 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