Secondary closure. Healing of a wound in which a gap is left between its edges. Union occurs by granulation tissue formation from the base and the sides. This requires epithelial migration, collagen deposition, contraction, and remodeling during healing.<\/p>\n
The healing of an infected wound or ulcer, which takes place slowly and may leave a permanent scar.<\/p>\n
Healing by granulation or indirect union. Granulation tissue is formed to fill the gap between the edges of the wound with a thin layer of fibrinous exudate. Granulation tissue also excludes bacteria from the wound and brings new blood vessels to the injured part. Healing by second intention takes longer than healing by primary intention and typically results in the formation of a prominent scar; wounds that heal by second intention show signs of failure if the wound loses the normal red-gray appearance of granulation tissue and becomes pale, dry, or insubstantial. When granulations first form at the top instead of the bottom of the wound, the base of the wound may have to be kept open with wicks or drains to promote healthy tissue repair.<\/p>\n
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Secondary closure. Healing of a wound in which a gap is left between its edges. Union occurs by granulation tissue formation from the base and the sides. This requires epithelial migration, collagen deposition, contraction, and remodeling during healing. The healing of an infected wound or ulcer, which takes place slowly and may leave a permanent […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-3969","post","type-post","status-publish","format-standard","hentry","category-h"],"yoast_head":"\n