{"id":6156,"date":"2020-02-14T08:02:00","date_gmt":"2020-02-14T08:02:00","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=6156"},"modified":"2022-10-18T06:53:59","modified_gmt":"2022-10-18T06:53:59","slug":"osteopontin","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/osteopontin\/","title":{"rendered":"Osteopontin"},"content":{"rendered":"<p>Noncollagenous protein with an arginine\u2010glycine\u2010aspartic acid (RGD) tripeptide sequence having specificity for cell surface antigens. It is found in the lamina limitans of the bone surface, possibly playing a role in bone mineralization and attachment of osteoblasts and osteoclasts to bone matrix. It forms a cross\u2010link with fibronectin and is found in cement lines, suggesting a function as a biologic matrix\u2010bonding agent.<\/p>\n<hr \/>\n<p>An extracellular matrix glycoprotein (approximate molecular weight 44 to 64 kD). It has been implicated in the pathophysiology of inflammatory, autoimmune, and malignant disorders as well as in wound repair.<\/p>\n<hr \/>\n<p>An extracellular matrix glycoprotein (approximate molecular weight 44 to 64 kD). It has been implicated in the pathophysiology of inflammatory, autoimmune, and malignant disorders as well as in wound repair.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Noncollagenous protein with an arginine\u2010glycine\u2010aspartic acid (RGD) tripeptide sequence having specificity for cell surface antigens. It is found in the lamina limitans of the bone surface, possibly playing a role in bone mineralization and attachment of osteoblasts and osteoclasts to bone matrix. It forms a cross\u2010link with fibronectin and is found in cement lines, suggesting [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[],"class_list":["post-6156","post","type-post","status-publish","format-standard","hentry","category-o"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Osteopontin - Definition of Osteopontin<\/title>\n<meta name=\"description\" content=\"Noncollagenous protein with an arginine\u2010glycine\u2010aspartic acid (RGD) tripeptide sequence having specificity for cell surface antigens. It is found in the lamina limitans of the bone surface, possibly playing a role in bone mineralization and attachment of osteoblasts and osteoclasts to bone matrix. It forms a cross\u2010link with fibronectin and is found in cement lines, suggesting a function as a biologic matrix\u2010bonding agent.An extracellular matrix glycoprotein (approximate molecular weight 44 to 64 kD). It has been implicated in the pathophysiology of inflammatory, autoimmune, and malignant disorders as well as in wound repair.An extracellular matrix glycoprotein (approximate molecular weight 44 to 64 kD). 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