{"id":6710,"date":"2020-02-17T04:50:50","date_gmt":"2020-02-17T04:50:50","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=6710"},"modified":"2020-02-17T04:50:50","modified_gmt":"2020-02-17T04:50:50","slug":"polyglycolic-acid-pga","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/polyglycolic-acid-pga\/","title":{"rendered":"Polyglycolic acid (PGA)"},"content":{"rendered":"<p>Biodegradable, rigid thermoplastic polymer of glycolic acid and the simplest linear, aliphatic polyester used as a material for the synthesis of absorbable sutures and barrier membranes and as a carrier for bone morphogenetic proteins (BMPs). When exposed to physiologic conditions, PGA is degraded by random hydrolysis and apparently also broken down by certain enzymes, especially those with esterase activity. The degradation product, glycolic acid, is nontoxic and can enter the tricarboxylic acid cycle, after which it is excreted as water and carbon dioxide. A part of the glycolic acid is also excreted by urine.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biodegradable, rigid thermoplastic polymer of glycolic acid and the simplest linear, aliphatic polyester used as a material for the synthesis of absorbable sutures and barrier membranes and as a carrier for bone morphogenetic proteins (BMPs). When exposed to physiologic conditions, PGA is degraded by random hydrolysis and apparently also broken down by certain enzymes, especially [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-6710","post","type-post","status-publish","format-standard","hentry","category-p"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Polyglycolic acid (PGA) - Definition of Polyglycolic acid (PGA)<\/title>\n<meta name=\"description\" content=\"Biodegradable, rigid thermoplastic polymer of glycolic acid and the simplest linear, aliphatic polyester used as a material for the synthesis of absorbable sutures and barrier membranes and as a carrier for bone morphogenetic proteins (BMPs). When exposed to physiologic conditions, PGA is degraded by random hydrolysis and apparently also broken down by certain enzymes, especially those with esterase activity. The degradation product, glycolic acid, is nontoxic and can enter the tricarboxylic acid cycle, after which it is excreted as water and carbon dioxide. A part of the glycolic acid is also excreted by urine.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.healthbenefitstimes.com\/glossary\/polyglycolic-acid-pga\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Polyglycolic acid (PGA) - Definition of Polyglycolic acid (PGA)\" \/>\n<meta property=\"og:description\" content=\"Biodegradable, rigid thermoplastic polymer of glycolic acid and the simplest linear, aliphatic polyester used as a material for the synthesis of absorbable sutures and barrier membranes and as a carrier for bone morphogenetic proteins (BMPs). When exposed to physiologic conditions, PGA is degraded by random hydrolysis and apparently also broken down by certain enzymes, especially those with esterase activity. The degradation product, glycolic acid, is nontoxic and can enter the tricarboxylic acid cycle, after which it is excreted as water and carbon dioxide. 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When exposed to physiologic conditions, PGA is degraded by random hydrolysis and apparently also broken down by certain enzymes, especially those with esterase activity. The degradation product, glycolic acid, is nontoxic and can enter the tricarboxylic acid cycle, after which it is excreted as water and carbon dioxide. 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