{"id":8477,"date":"2020-02-25T07:50:18","date_gmt":"2020-02-25T07:50:18","guid":{"rendered":"https:\/\/www.healthbenefitstimes.com\/glossary\/?p=8477"},"modified":"2022-07-13T06:50:28","modified_gmt":"2022-07-13T06:50:28","slug":"transforming-growth-factor-tgf","status":"publish","type":"post","link":"https:\/\/www.healthbenefitstimes.com\/glossary\/transforming-growth-factor-tgf\/","title":{"rendered":"Transforming growth factor (TGF)"},"content":{"rendered":"<p>Any of several proteins secreted by transformed cells that stimulate growth of normal cells, although not causing transformation. TGFalpha or TGF\u2010A is a 50\u2010amino acid polypeptide which binds to the epidermal growth factor receptor (EGFR) and also stimulates growth of microvascular endothelial cells. TGF\u2010beta or TGF\u2010B exists as several subtypes, all of which are found in hematopoietic tissue and promote wound healing.<\/p>\n<hr \/>\n<p>Polypeptide growth factor that competitively binds to epidermal growth factor (EGF) receptors. This molecule can promote growth of fibroblasts in cell cultures, thus \u201ctransforming\u201d normal cells into those with the abnormal properties of malignant cells.<\/p>\n<hr \/>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Any of several proteins secreted by transformed cells that stimulate growth of normal cells, although not causing transformation. TGFalpha or TGF\u2010A is a 50\u2010amino acid polypeptide which binds to the epidermal growth factor receptor (EGFR) and also stimulates growth of microvascular endothelial cells. TGF\u2010beta or TGF\u2010B exists as several subtypes, all of which are found [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-8477","post","type-post","status-publish","format-standard","hentry","category-t"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Transforming growth factor (TGF) - Definition of Transforming growth factor (TGF)<\/title>\n<meta name=\"description\" content=\"Any of several proteins secreted by transformed cells that stimulate growth of normal cells, although not causing transformation. TGFalpha or TGF\u2010A is a 50\u2010amino acid polypeptide which binds to the epidermal growth factor receptor (EGFR) and also stimulates growth of microvascular endothelial cells. TGF\u2010beta or TGF\u2010B exists as several subtypes, all of which are found in hematopoietic tissue and promote wound healing.Polypeptide growth factor that competitively binds to epidermal growth factor (EGF) receptors. 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TGF\u2010beta or TGF\u2010B exists as several subtypes, all of which are found in hematopoietic tissue and promote wound healing.Polypeptide growth factor that competitively binds to epidermal growth factor (EGF) receptors. 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