XXX syndrome

XXX syndrome is a disorder in which affected females have three X chromosomes. It may also be referred to as Chromosome X, Triplo-X, and Chromosome 47, XXX karyotype. XXX syndrome was first described by P. A. Jacobs in the Lancet in 1959. It is the most frequent X chromosomal anomaly in females. The incidence of XXX syndrome is 0.3-1 per 1000 newborn females.


 


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