Melanosis coli

A condition in which the colon’s mucous membrane is abnormally pigmented with melanin (a dark brown or black pigment that normally occurs in the skin, hair, and other tissues), due to prolonged use of certain stimulant types of laxatives, such as senna and castor oil.


A benign brown or black discoloration of the colon that results from the use of laxatives, such as senna derivatives.


The colon lining can become discolored in shades of black or brown. This condition, known as melanosis coli, is linked to persistent constipation and the extended usage of specific laxative medications like senna, rhubarb, and cascara.


This discoloration is frequently observed in older individuals and typically doesn’t exhibit any symptoms. It tends to fade away once the use of laxatives is discontinued. In rare cases, it can be connected to colon cancer.


Dark coloring of the colon’s inner lining, which can result from the use of laxatives.


 


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