Epidermal growth factor

Mitogenic polypeptide that promotes growth and differentiation, is essential in embryogenesis, and is important in wound healing.


A protein of 53 amino acids that greatly increases growth/reproduction of epidermal (skin) cells. This protein also increases growth of wool in sheep. High concentrations of epidermal growth factor are found in human tears. EGF was discovered by Stanley Cohen.


A polypeptide that stimulates growth of several different cells, including keratinocytes. It has been used experimentally to promote wound healing.


 


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