NSAIDs include aspirin and aspirin-like drugs (Indacin, Motrin, Advil, Clinoril, Naprosyn). They block the enzyme responsible for the body’s synthesis of prostaglandins and related substances. Blocking synthesis of some prostaglandins can cause salt and water retention by the kidney and thereby increase blood pressure.
Aspirin, indomethacin, and phenylbutazone. These drugs block the action of cyclooxygenase by acetylating the enzyme. While occasional use of these drugs for the occasional injury or headache is harmless, long-term, chronic use can result in untoward effects. Long-term, chronic use of aspirin, for example, can affect vascular competence and blood clotting. People consuming large amounts of aspirin over long periods of time may find an increase in bruises (subcutaneous hemorrhages). Small contact injuries that normally would not result in a bruise will do so in these people. Gastric bleeding is another possible complication with long-term, chronic aspirin ingestion. Aplastic anemia can result from long-term phenylbutazone therapy.
Medications containing no steroid ingredients that relieve and treat inflammatory conditions such as arthritis.
Drugs used to relieve symptoms associated with arthritis and other painful conditions. Nonsteroidal anti-inflammatory drugs, or NSAIDs, are used to relieve inflammation, swelling, stiffness, and joint pain. They are also used to treat attacks of gout; bursitis; tendinitis; sprains, strains, or other injuries; and menstrual cramps. In addition to their pain- relieving properties, some NSAIDs, including aspirin and ibuprofen, have fever-reducing properties. Aspirin should not be given to children under i8 because of the risk of contracting Reye syndrome, a potentially fatal disease.
A drug that has analgesic, anti-inflammatory, and antipyretic actions. NSAIDs are used to treat acute and chronic pain (e.g., of injuries, arthritis, and dysmenorrhea), to reduce inflammation, and to prevent complications in serious illness such as sepsis.
A class of medications that includes aspirin that reduces inflammatory responses without using steroids.
Painkilling medications that lessen the swelling of injured blood vessels; also called NSAIDs.
Within the realm of medicinal offerings, both readily available without a prescription and those necessitating a prescription, exist with the purpose of mitigating inflammation and alleviating pain.
A collection of medications, also referred to as NSAIDs, that generate pain relief (analgesia) and decrease inflammation in joints and soft tissues like muscles and ligaments.
Nonsteroidal anti-inflammatory drugs (NSAIDs) find extensive use in alleviating symptoms arising from various forms of arthritis, including rheumatoid arthritis, osteoarthritis, and gout. While they don’t provide a cure or halt disease progression, they effectively enhance the mobility of afflicted joints and alleviate pain and stiffness. NSAIDs are also employed to treat conditions like back pain, menstrual discomfort, headaches, pain following minor surgical procedures, and injuries to soft tissues.
NSAIDs function by inhibiting the activity of the enzyme cyclooxygenase (COX), which plays a role in the body’s synthesis of prostaglandins (chemicals responsible for inflammation and the transmission of pain signals to the brain, while also safeguarding the stomach lining). Many NSAIDs block both COX-2 (resulting in an anti-inflammatory response) and COX-1 (causing stomach discomfort). The development of COX-2 inhibitors was aimed at selectively targeting COX-2, thereby minimizing the potential for stomach irritation.
NSAIDs have the potential to lead to various side effects. These include feelings of nausea, issues with digestion, stomach bleeding, fluid retention, and, on rare occasions, peptic ulcers. Additionally, they can exacerbate heart failure or kidney failure. In contrast, COX-2 inhibitors tend to cause less irritation to the gastrointestinal system compared to other NSAIDs.