Bone resorption and dissolution, involving the loss or removal of calcium, as part of an ongoing disease process.
Destruction of bone tissue by osteoclasts.
Loss of bone calcium.
Degeneration and dissolution of bone caused by disease, inadequate blood supply, or infection.
Dissolution of bone through disease, commonly by infection or loss of the blood supply (ischemia) to the bone. In acro-osteolysis the terminal bones of the fingers or toes are affected: a common feature of some disorders involving blood vessels (including Raynaud’s disease), scleroderma, and systemic lupus erythematosus.
A softening and destruction of bone without compensatory osteoclastic activity. Osteolysis occurs within compact bone and results from a breakdown of the organic matrix and subsequent leaching out of the inorganic fraction. The condition is probably caused by localized metabolic disturbances, vascular changes, or the release of hydrolytic enzymes by osteocytes.
The degeneration and depletion of bone triggered by inflammation induced by tiny fragments of debris originating from a prosthetic device.