Reiter’s syndrome

A condition of unknown cause, usually seen in young men, characterized by urethritis, arthritis, conjunctivitis, and mucocutaneous lesions.


An illness which may be sexually transmitted and affects mainly men, causing arthritis, urethritis and conjunctivitis at the same time [Described 1916. After Hans Conrad Reiter (1881-1969), German bacteriologist and hygienist.]


Inflammatory syndrome of unknown etiology, occurring predominantly in males. It usually begins several weeks after either a gastrointestinal or sexually-transmitted infection with the onset of conjunctivitis, urethritis, and arthritis, especially of the ankles and sacroilliac joints. Treatment involves nonsteroidal anti-inflammatory agents, especially phenylbutazone.


A form of inflammatory arthritis transmitted by sexual contact and the organisms that cause dysentery; it occurs in people who have a genetic susceptibility to it. Typically, the first symptom in men is a penile discharge. Subsequent symptoms for men or women include painful joints often in the knee, heel, or fingers. An eye inflammation called conjunctivitis and a skin rash similar in appearance to psoriasis may follow. An episode of Reiter syndrome may last a few weeks or several months. The symptoms may appear once or return. The joints are rarely damaged permanently. When severe, Reiter syndrome can cause tenderness and pain in the joints and is generally treated with pain-relieving medication such as nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin and ibuprofen.


A disease of men involving diarrhea, inflammation of the urethra and conjunctiva and arthritis. Horny areas may develop on the skin. The symptoms resemble those of gonorrhea. No causative agent has been positively identified, although a virus may be implicated.


A condition probably caused by an immunological response to a virus, in which the patient has urethritis, arthritis and conjunctivitis. The skin may also be affected by horny areas which develop in it. This is the most common cause of arthritis in young men. It usually develops in people who have a genetic predisposition for it: around 80 per cent of sufferers have the HLA B27 tissue type. Treatment is symptomatic with analgesia and non-steroidal anti-inflammatory drugs (NSAIDS).


An assemblage of manifestations comprising arthritis, inflammation of the urethra, and conjunctivitis, known as a delayed consequence of Shigella flexneri infection, is termed a syndrome. This syndrome was initially documented by Hans Reiter, a German physician, in the year 1918.


Reiter’s syndrome is characterized by a blend of urethritis, reactive arthritis, and conjunctivitis. Uveitis might also occur alongside these symptoms. This syndrome tends to affect men more frequently than women.


The underlying cause of Reiter’s syndrome stems from an immune response, typically emerging in individuals with a genetic susceptibility. The majority of patients possess the HLA-B27 tissue type. Infection serves as the trigger for the syndrome’s onset, commonly stemming from conditions like nongonococcal urethritis or occasionally from bacillary dysentery.


Typically, Reiter’s syndrome commences with a discharge from the urethra, succeeded by the occurrence of conjunctivitis, and subsequently arthritis. The arthritis tends to impact one or two joints, frequently affecting the knee and/or ankle, often accompanied by fever and a sense of general discomfort. These episodes can persist for extended periods, spanning several months. Inflammation can also extend to tendons, ligaments, and the tissues on the soles of the feet. Additionally, skin rashes are a prevalent feature.


Diagnosis relies on the presented symptoms. Pain relief and reduction of inflammation are achieved through analgesic medications (painkillers) and nonsteroidal anti-inflammatory drugs (NSAIDs), which might need to be taken over an extended period. Recurrences are observed in approximately one third of cases.


 


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