A condition in which cartilage, ligaments and other fibrous tissue become dark as a result of a metabolic disorder, and in which the urine turns black on exposure to air.
Condition marked by the accumulation of brown-black pigment in cartilage and other connective tissue, usually due to phenol poisoning.
The presence of brown-black pigment in the skin, cartilage, and other tissues due to the abnormal accumulation of homogentisic acid that occurs in the metabolic disease alcaptonuria.
A rare condition in which the ligaments and cartilages of the body, and sometimes the conjunctive, become stained by dark brown or black pigment. This may occur in chronic carbolic poisoning, or in a congenital disorder of metabolism in which the individual is unable to completely break down tyrosine in protein molecules the intermediate product, homogentisic acid, appearing in the urine, this being known as alkaptonuria.
A rare illness whose hallmark is abnormally dark pigmentation of the skin, urine, and connective tissues. There are two variants: Endogenous ochronosis, also known as alkaptonuria, is familial (transmitted genetically in autosomal recessive inheritance). Exogenous ochronosis results from exposure to specific drugs or chemicals, such as hydroquinone or phenol.
A rare genetic disorder that commonly results in the development of arthritis during adulthood is known as hereditary arthropathy.