A condition in which the bony spaces become hardened as a result of persistent inflammation.
Abnormal increase in bone density, resulting from a variety of diseases, including tumor formation, inadequate blood supply, or chronic infection.
A rare hereditary disorder of bone formation characterized by an abnormal increase in bone density, which results in massive, fragile bones. With osteosclerosis, the long bones of the extremities are thickened and expand into trumpetlike shapes. In some cases, the increased thickness of the bones fills the spaces containing bone marrow, the tissue that produces red blood cells; this can cause severe anemia, which may prove fatal. Bone overgrowth at the base of the skull may cause pressure on certain structures of the eye and produce blindness. Pressure on the auditory nerves can result in deafness.
An abnormal increase in the density of bone, as a result of poor blood supply, chronic infection, or tumor. The affected bone is more opaque to X-rays than normal bone.
Elevated bone density is evident on X-rays as a region of pronounced whiteness. Localized osteosclerosis can stem from a significant injury causing bone compression, the joint ailment osteoarthritis, chronic osteomyelitis (bone infection), or the presence of an osteoma (benign bone tumor). Osteosclerosis is observed throughout the body in the hereditary bone condition known as osteopetrosis.