Category: R
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Reverse transcriptase
Viral enzyme that catalyses the conversion of mRNA into cDNA. Also known as RNA-directed DNA polymerases. A class of enzymes first discovered to be present in RNA tumor-virus which allows the synthesis of DNA using the RNA present in the virus as a template. This is the reverse of what normally happens and hence the…
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Retinol-biding protein
A plasma protein which specifically binds retinol (the alcohol form of vitamin A) and prevents it from being excreted. In vitamin A sufficiency, all the RBP is bound to retinol, in a 1:1 complex, but in vitamin A deficiency the protein may become partially desaturated, so that the ratio of protein to retinol then exceeds…
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Retinoids
Compounds chemically related to, or derived from, vitamin A, which display some of the biological activities of the vitamin, but have lower toxicity; they are used for treatment of severe skin disorders and some cancers. A group of biologically active compounds that are chemical derivatives of vitamin A. Among other effects on living cells, some…
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Retinal maculopathy
Deterioration of the macula (central region of the retina) which occurs progressively in older people, thus irreversibly impairing vision. Thought to be exacerbated by pro-oxidant action such as by oxygen free radicals.
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Retinal (retinaldehyde), retinene, retinoic acid, retinol
Vitamers of vitamin A.
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Reticulocyte
Immature precursor of the red blood cell in which the remains of the nucleus are visible as a reticulum. Very few are seen in normal blood as they are retained in the marrow until mature, but on remission of anaemia, when there is a high rate of production, reticulocytes appear in the bloodstream (reticulocytosis). Immature…
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Respiratory quotient (RQ)
Ratio of the volume of carbon dioxide produced when a substance is oxidised, to the volume of oxygen used. The oxidation of carbohydrate results in an RQ of 1.0; of fat, 0.7; and of protein, 0.8. Ratio of the amount of carbon dioxide produced to the amount of oxygen consumed at cellular level. The ratio…
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Renal threshold
Concentration of a compound in the blood above which it is not reabsorbed by the kidney, and so is excreted in the urine. Concentration of a substance in plasma at which it is excreted in urine. The concentration at which a substance in the blood normally not excreted by the kidney begins to appear in…
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Renal plasma flow
Rate of passage of plasma through the kidneys, directly related to glomerular filtration rate.
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Relative protein value (RPV)
A measure of protein quality.