Category: R

  • Reverse transcriptase

    Viral enzyme that catalyses the conversion of mRNA into cDNA. Also known as RNA-directed DNA polymerases. A class of enzymes first discovered to be present in RNA tumor-virus which allows the synthesis of DNA using the RNA present in the virus as a template. This is the reverse of what normally happens and hence the…

  • Retinol-biding protein

    A plasma protein which specifically binds retinol (the alcohol form of vitamin A) and prevents it from being excreted. In vitamin A sufficiency, all the RBP is bound to retinol, in a 1:1 complex, but in vitamin A deficiency the protein may become partially desaturated, so that the ratio of protein to retinol then exceeds…

  • Retinoids

    Compounds chemically related to, or derived from, vitamin A, which display some of the biological activities of the vitamin, but have lower toxicity; they are used for treatment of severe skin disorders and some cancers. A group of biologically active compounds that are chemical derivatives of vitamin A. Among other effects on living cells, some…

  • Retinal maculopathy

    Deterioration of the macula (central region of the retina) which occurs progressively in older people, thus irreversibly impairing vision. Thought to be exacerbated by pro-oxidant action such as by oxygen free radicals.  

  • Retinal (retinaldehyde), retinene, retinoic acid, retinol

    Vitamers of vitamin A.  

  • Reticulocyte

    Immature precursor of the red blood cell in which the remains of the nucleus are visible as a reticulum. Very few are seen in normal blood as they are retained in the marrow until mature, but on remission of anaemia, when there is a high rate of production, reticulocytes appear in the bloodstream (reticulocytosis). Immature…

  • Respiratory quotient (RQ)

    Ratio of the volume of carbon dioxide produced when a substance is oxidised, to the volume of oxygen used. The oxidation of carbohydrate results in an RQ of 1.0; of fat, 0.7; and of protein, 0.8. Ratio of the amount of carbon dioxide produced to the amount of oxygen consumed at cellular level. The ratio…

  • Renal threshold

    Concentration of a compound in the blood above which it is not reabsorbed by the kidney, and so is excreted in the urine. Concentration of a substance in plasma at which it is excreted in urine. The concentration at which a substance in the blood normally not excreted by the kidney begins to appear in…

  • Renal plasma flow

    Rate of passage of plasma through the kidneys, directly related to glomerular filtration rate.  

  • Relative protein value (RPV)

    A measure of protein quality.