Endothelial cell

The main type of cell found in the inside lining of blood vessels, lymph vessels, and the heart.


These are the flat, sort of plate-shaped cells that line the surface of all blood vessels, heart, and lymphatics within the body. Endothelial cells possess transmembrane (i.e., through the cell membrane) molecules known as adhesion molecules, which selectively allow the passage (from bloodstream to tissues) of some molecules (e.g., leukocytes, monocytes, hormones, etc.). Endothelial cells are packed much tighter together in the capillaries that provide blood to the brain. This tighter packing limits the size and kind of molecules that can pass into the brain. This blood-brain barrier serves to protect the sensitive brain tissue from pathogens or harmful molecules.


One of the flat cells that form the lining of the blood and lymph vessels.


 


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