A toxin produced with an organism, liberated only when the organism disintegrates.
A lipopolysaccharide (fat/sugar complex; poison, also known as LPS) which forms an integral part of the cell wall of gram negative bacteria. It is only released when the cell is ruptured. It can cause, among other things, septic shock and tissue damage. Pharmaceutical preparations are routinely tested for the presence of endotoxins. This is one reason why pharmaceuticals must be prepared in a sterile environment.
Toxins retained within a bacterial cell until freed by the disruption of the cell.
A toxic substance released after the death of some bacterial cells.
Toxin confined within a bacterium or other microorganism and released only when the microorganism is broken down or dies. Endotoxins may cause fever, chills, shock, and other symptoms in the infected person.
A poisonous substance in the walls of gram-negative bacteria that produces a systemic inflammatory response and sepsis.
A toxin liberated during the destruction of bacterial or other microbial cells.
A poisonous material shed by the outer membranes of certain types of disease-causing bacteria, particularly when they are disturbed or destroyed. Endotoxin is responsible for the symptoms arising from infection with these bacteria. Small amounts of endotoxin produce fever and lower resistance to infection. Large amounts can lead to internal bleeding, heart failure, low blood pressure, and severe diarrhea.
A poison generally harmful to all body tissues, contained within a bacterium and released only when the bacterial cell is broken down or dies and disintegrates.
A poison produced by certain gram-negative bacteria; it is released after the micro-organisms die. Endotoxins can cause fever and shock, the latter by rendering the walls of blood vessels permeable so that fluid leaks into the tissues, with a consequent sharp fall in blood pressure.
A lipopolysaccharide that is part of the cell wall of gram-negative bacteria. It binds with CD14 receptors on leukocytes. The linkage stimulates the release of interleukin- 1, tumor necrosis factor, and other cytokines, affecting inflammation, the specific immune response, vascular tone, hematopoiesis, and wound healing. When large amounts of lipopolysaccharides are present, the clinical state of sepsis or systemic inflammatory response syndrome occurs. Endotoxins are still active even after bacteria are destroyed; thus, in treating some infections, the positive effects of antibiotics may be delayed or absent.
Endotoxins are harmful substances generated by specific bacteria, which aren’t liberated until those bacteria die. When these endotoxins are released in individuals with an infection, they provoke a fever. They also increase the permeability of the capillaries, which are the tiniest blood vessels, triggering fluid to seep into the adjacent tissues. This process can occasionally cause a drop in blood pressure, leading to a condition known as endotoxic shock.
A toxin that is released from a germ only when the germ breaks down. This is distinct from the typical poison that the germ produces and secretes into the blood to cause illness.