A form of ichthyosis, erythrokeratodermia progressiva symmetrica (EPS) is a very rare hereditary skin disorder characterized by keratotic (hardened red) plaques distributed over the body and the extremities. However, the chest and abdomen area are normally void of any plaques. Cornification normally appears during the first year of life; some cases involving EPS have been documented to disappear spontaneously later in life.