Estradiol

Is the predominant sex hormone present in females, also called oestradiol.

The major natural estrogen secreted by the ovaries, testes, and placenta.

Most powerful naturally occurring female hormone.

A naturally occurring estrogen that is formed by the ovary, placenta, testes, and adrenal cortex.

A hormone used to treat a lack of estrogen. Estradiol is chiefly produced in the ovaries, but also is produced in the placenta, testis, and adrenal cortex. When estrogen is lacking in a woman after menopause or removal of the ovaries, estradiol may be prescribed for hormone replacement therapy. It is also used to treat prostate cancer and osteoporosis, and it is used in some oral contraceptives.

A steroid produced by the ovary and possessing estrogenic properties. Large quantities are found in the urine of pregnant women and of mares and stallions, the latter two serving as sources of the commercial product that is used to treat estrogen deficiencies, e.g. menopause. Estradiol is effective when given subcutaneously or intramuscularly but not when given orally. It is converted to estrone in the body.

Estradiol is the primary and most crucial estrogen hormone, vital for maintaining the healthy functioning of the female reproductive system and promoting breast development. When synthesized artificially, estradiol is utilized to alleviate the symptoms and complications of menopause and to stimulate sexual development in cases of female hypogonadism, which involves underactivity of the ovaries.