An inherited condition that results in extremely large stature. It is caused by inheritance of genes for height and abnormal endocrine secretions resulting in the lack of closure of the epiphysis of long bones, and the eosinophil cells of the anterior pituitary gland secrete an excess of the principal growth hormone.
A condition in which someone grows very tall, caused by excessive production of growth hormone by the pituitary gland.
A condition involving abnormal growth, in height and weight.
Condition characterized by excessive size, caused most frequently by over-secretion of growth hormone from the pituitary gland. Treatment is by irradiation or removal of the pituitary gland.
Abnormal growth causing excessive height, most commonly due to over secretion during childhood of growth hormone (somatotropin) by the pituitary gland. In eunuchoid gigantism the tall stature is due to delayed puberty, which results in continued growth of the long bones before their growing ends (epiphyses) fuse.
Excessive growth (mainly in height) caused by overproduction, during childhood or adolescence, of growth hormone by a tumour of the pituitary gland. Untreated, the affected individual may die in early adulthood. Sometimes the tumour appears after the individual has stopped growing and the result then is acromegaly rather than gigantism.
The excessive development of the body or a body part.
The abnormal proliferation, particularly in stature, arising from the excessive production of growth hormone during childhood or adolescence due to a pituitary tumor. If left untreated, the tumor eventually causes the demise of the pituitary gland, leading to early adulthood mortality. It is crucial to note that if the tumor emerges after the cessation of growth, the resultant condition is acromegaly, rather than gigantism.
Excessive growth, particularly in height, during childhood or adolescence is caused by an overproduction of growth hormone due to a pituitary gland tumor. If left untreated, this tumor may exert pressure on other hormone-producing cells in the gland, leading to symptoms of hormone deficiency.
Individuals with gigantism can undergo treatment with a growth hormone-blocking drug like bromocriptine. Alternatively, they may require surgery or radiotherapy to eliminate or destroy the pituitary tumor.
A condition characterized by unusually large size and height, often exceeding 79 inches, resulting from excessive production of growth hormone by the anterior part of the pituitary gland in the brain.