A congenital endocrine disorder caused by failure of the ovaries to respond to pituitary hormone (gonadotropin) stimulation. Clinically there is amenorrhea, failure of sexual maturation, and usually short stature. About one third of these patients have webbing of the neck and may have cubitus valgus. Intelligence may be impaired.
Gonadal dysgenesis refers to the abnormal development of the gonads, which includes the testes and ovaries. This condition is a characteristic feature of Turner’s syndrome.