Kupffer cells

Are resident macrophages of the liver and play an important role in its normal physiology and homeostasis as well as participating in the acute and chronic responses of the liver to toxic compounds.


Phagocytic cells that line the sinusoids of the liver. They are particularly concerned with the formation of bile and are often seen to contain fragments of red blood cells and pigment granules derived from the breakdown of hemoglobin.


Star-shaped cells present in the blood sinuses of the liver. They form part of the reticulo-endothelial system and are to a large extent responsible for the breakdown of haemoglobin into the bile pigments.


 


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