Mikulicz disease is one of the autoimmune disorders with Sjogren syndrome and systemic lupus erythematosis. With Mikulicz disease there is chronic bilateral enlargement of glands in the neck area (e.g., lacrimal, parotid, and salivary glands) similar to what might be expected with the mumps. Other glands in the area of face and neck may be involved as well. Although originally believed to be relatively benign, it is associated with decreased or absent production of tears (lacrimation) and dryness of the mouth (xerostomia). Mikulicz disease may be accompanied by chronic lymphyocytic infection (National Organization of Rare Diseases, Inc. [NORD], 1994).