Disorders caused by mutations affecting the mitochondria (components of cells that oxidize food for them) in the cells of the body. When genetic mutations affect the mitochondria, disruption in energy supply can be devastating. The most vulnerable cells are those requiring the most energy, such as those in the brain, heart, and skeletal muscles. Most mitochondrial diseases are inherited.
Any of hundreds of congenital illnesses that result from mutations in the DNA of mitochondria. Mitochondrial diseases are transmitted from mother to child.