Mitogen

A substance that causes DNA synthesis, blast transformation, and mitosis in lymphocytes.


An agent that triggers mitosis, elicit all the signals necessary to induce cell proliferation.


A substance (e.g., growth factor, hormone, etc.) that initiates cell division within the body. For example, most Angiogenic Growth Factors (e.g., fibroblast growth factor) stimulate cell division of the endothelial cells which line blood vessel walls.


A plant-derived protein used in the laboratory to stimulate cell division (mitosis). It is frequently used in vitro to study the proliferation of lymphocytes from blood drawn during a research study. The most commonly used mitogens are phytohemagglutinin and concanavalin A.


 


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