Monoclonal antibody

An antibody which can be easily made in the laboratory by a single clone of cells. It may be useful in the treatment of cancer.


Antibody produced from a special cell (hybridoma) that is very specific for a particular location in the body. Monoclonal antibodies are used in many areas of medicine for diagnostic tests and are being tested experimentally as anticancer agents.


Aantibodies that are made from a particular cell clone, all of which have similar molecules. They are used for various research and treatment purposes.


An antibody produced in large quantities by a single cell directed for use against a specific antigen. If the body produces an excess of a monoclonal antibody, this may be a sign of a plasma cell disorder such as multiple myeloma, a type of cancer.


A class of diagnostic and therapeutic agents (substance) which is produced biologically (grown) in a laboratory using a clone of a single special kind of cell (hybridoma) which has the ability to produce a continuous supply of identical antibodies. Each kind of MAB recognizes only one kind of antibody. MAB are used in identifying bacteria, viruses, certain tumors, and hormones, in diagnosing infectious diseases, and in blood typing. They are also used to treat certain infections, and are being studied for treatment of cancer.


A type of antibody, specific to a certain antigen, created in the laboratory from hybridoma cells. Because they are derived from a single cell line and raised against a single antigen, monoclonal antibodies are highly specific. Diagnostically, they are used to identify microorganisms, white blood cells, hormones, and tumor antigens. In patient care, they are used to treat transplant rejection, certain cancers, and autoimmune diseases.


An antibody generated by the genetically identical descendants of a solitary cloned cell responsible for antibody production.


A laboratory-engineered antibody designed to specifically neutralize a single antigen (foreign protein).


Monoclonal antibodies are created within a laboratory setting by stimulating the proliferation of a large population of identical, antibody-producing cells. This technique effectively allows for the customization of antibodies to specifically target a particular antigen.


Monoclonal antibodies find utility in various domains, including the examination of human cells, hormones, and microorganisms, as well as the advancement of vaccines. Furthermore, they have gained significance in the diagnosis and treatment of specific types of cancer. Genetically engineered monoclonal antibodies are purposefully designed to attach to proteins present on the surface of particular cancer cells, effectively labeling them for destruction. By recognizing these marked cells, the immune system can subsequently eliminate them.


 


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