A form of skin cancer, with irritating nodules.
Cutaneous T-cell lymphoma characterized by irregular shaped nodules and plaques on the trunk that spread to lymph nodes and internal organs.
A fairly rare form of chronic lymphoma affecting the skin and internal organs.
A rare cancer characterized by multiple scaly patches on the skin. Mycosis fungoides is a cancer of the T lymphocytes (a type of white blood cell) that affects the skin. Symptoms usually begin with generalized itching and the appearance of raised, reddened skin on any area of the body. The disease develops very slowly, and the raised patches on the skin may persist for years. A common treatment for mycosis fungoides is radiation therapy, although systemic chemotherapy and therapies designed to use the body’s immune system to fight the cancer are also used. Individuals can be treated with a combination of ultraviolet (UV) light and medications that sensitize the cells to UV light.
A disease that is a variety of reticulosis usually confined to the skin. Chronic irritating eruptions occur, resembling eczema or psoriasis. Purplish tumors develop and then ulcerate. The disease is fatal, though partial remission may be effected with anticancer drugs.
An old term for a chronic eruption of the skin characterized by erythematous itching plaques (raised patches on the skin resulting from the merging or enlargement of papules, which, if left untreated, eventually form tumours and ulcers. The disease is now known to be a form of cancer of lymphocytes called T-cell lymphoma. It may be responsive to photochemotherapy in its early stages and to radiotherapy when more advanced.
Cutaneous T-cell lymphoma, especially when the disease is first clinically apparent on the skin. The skin is marked by irregularly shaped macules, plaques, or nodules, which usually first appear on the trunk and may sometimes cause considerable itching. The rash may be difficult to diagnose or may be misdiagnosed as another form of dermatitis. Biopsy specimens may reveal atypical-appearing lymphocytes in the epidermis or collections of malignant lymphocytes in clusters called Pautrier’s micro abscesses. Eventually (e.g., 10 or more years after diagnosis), the malignant cells disseminate throughout the skin and into lymph nodes and internal organs.
Mycosis fungoides stands as the predominant form of cutaneous T-cell lymphoma, a type of lymphoma that primarily affects the skin. This low-grade lymphoma exhibits a gradual progression and typically remains localized to the skin. However, in approximately 10% of cases, it may advance to involve the lymph nodes and internal organs over time.
An uncommon form of lymphoma that predominantly targets the skin on the buttocks, back, or shoulders. The cause of this condition is not yet understood. In its least severe manifestation, mycosis fungoides generates a non-itchy, red, and scaly rash that could either expand gradually or persist without change for numerous years. In more advanced cases, there can be the formation of thickened skin patches, ulcers, and enlargement of lymph nodes.
Confirmation of diagnosis involves a skin biopsy. Treatment options might encompass PUVA, radiotherapy, nitrogen mustard, anticancer medications, and corticosteroid drugs.
A severe illness that progresses slowly and is marked by symptoms such as eczema patches, swelling, nodules, tumors, and ulcers. While it typically leads to fatal outcomes, there are instances where, for reasons not fully understood, the disease unexpectedly improves on its own.