Mindblown: a blog about philosophy.

A compound that inhibits the production of the adrenal steroids, the glucocorticoids. A drug that inhibits the production of cortisol in the adrenal cortex, resulting in an increase in ACTH production and thus (completing the feedback control cycle) greater synthesis of the chemical precursors of cortisol. Metyrapone is used to treat patients with cushing’s syndrome…

A beta blocker and antihypertensive.  

A quinazoline derivative that acts as a diuretic and an antihypertensive. A diuretic used to treat fluid retention (edema) and high blood pressure. It is administered by mouth; side-effects include headache, loss of appetite, and digestive upsets, and blood potassium levels may be reduced. A thiazide-type diuretic which is particularly effective when combined with a…

A derivative of para-amino benzoic acid used as an antiemetic. It is also a gastrointestinal tract (GI) stimulant.  

A selenium metabolite having anticancer activity.  

Accumulation of methyl malonic acid in the blood; can be due to a genetic error, but also is a characteristic of vitamin B12 deficiency. An inherited metabolic disease caused by inability to convert methylmalonic acid to succinic acid. Clinically, signs are failure to grow, mental retardation, and severe metabolic acidosis. One form of the disease…

A drug that is an antihypertensive and an anticholinergic compound. A drug that reduces blood pressure. It is administered by mouth or injection, and drowsiness commonly occurs during the first days of treatment. A centrally acting anti-hypertensive drug often used in conjunction with a diuretic. It is sometimes used to control high blood pressure, especially…

A hormone produced by the pars distalis of the anterior pituitary. It arises from the same gene product as ACTH. The function of this hormone in humans is unclear.  

A carrier for certain minerals such as zinc.  

Mammalian cell-surface enzymes that participate in the postsecretory processing and metabolism of neuropeptides and peptide hormones.