Mindblown: a blog about philosophy.

Space between tissues. The fluid-filled regions encompassing the cells within a specific tissue are referred to as intercellular spaces, also known as tissue space.  

Lipoprotein resulting from removal of triglycerides from very-low-density lipoproteins and chylomicrons. Plasma lipids bound to albumin, consisting of lipoproteins with less protein than high-density, but more than low-density, lipoproteins.  

The water that surrounds cells and is contained in the intracellular space. Plasma is part of this compartment and surrounds the red blood cells in the blood.  

Inflammation of the insulin-producing β cells of the pancreas.  

Insulin release by the β cells of the pancreas involves a number of interrelated metabolic reactions in both the cytosol and the mitochondria. The islet must sense that blood glucose levels are rising. This is a critical step in insulin release. The glucose-phosphorylating enzyme, glucokinase, serves this function. GLUT 2 transports glucose through the plasma…

A cytosolic compound that associates with proteins containing SH2 domains; that is, tyrosine phosphatase when insulin binds to its receptor on the cell membrane.  

Protein that is embedded in the plasma membrane of the insulin-sensitive cell. When insulin is bound to its receptor, a cascade of signals is generated that includes the movement of glucose transporters to the plasma membrane and the subsequent metabolism of the incoming glucose. Mutations in the genes for the receptor phenotype as diabetes mellitus.…

A small instrument that senses changes in blood glucose and delivers insulin subcutaneously so as to maintain an optimal insulin-glucose relationship. An appliance for delivering insulin to people with type 1 diabetes. The pump steadily injects insulin into the body in a pattern that is similar to the way the pancreas normally releases insulin into…

Water lost through the skin and through the lungs that is not noticed by the individual.  

A phospholipid in the plasma membrane that releases phosphoinositol when stimulated by phospholipase C.