A class of synthetic, broadspectrum antibacterial agents that exhibit bactericidal action.
A drug used to treat Gram-negative and Gram-positive bacterial infections of the respiratory and urinary tracts and of the gastro-intestinal system.
A group of chemically related synthetic antibiotics. Examples include nalidixic acid, ciprofloxacin and norfloxacin which are effective in treating uncomplicated urinary-tract, respiratory-tract and gastrointestinal infections. They are usually effective against gram-negative and gram-positive bacteria. Many staphylococci including methicillinresistant staphylococcus aureus (MRSA) are resistant to quinolones. This group of drugs has a range of potentially troublesome side-effects including nausea, vomiting, dyspepsia, abdominal pain, diarrhoea, dizziness, sleep disorders and pruritus.
Any of a class of antibiotics that inhibit bacterial DNA gyrase. Commonly prescribed agents include ciprofloxacin, levofloxacin, norfloxacin, and ofloxacin.
A cluster of artificial antimicrobial medications, initially derived from quinine, falls under the category of quinolones. Among these, nalidixic acid holds the distinction of being the first quinolone to receive clinical approval for therapeutic application.