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Thrombotic thrombocytopenic purpura

by Glossary
November 28, 2022
in T
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A rare life-threatening disease marked by widespread aggregation of platelets throughout the body, neurological dysfunction, and renal insufficiency. The disease is triggered by a deficiency of an enzyme that cleaves von Willebrand factor (a blood clotting protein). This deficiency results in blood clots in small blood vessels throughout the body. Shifting neurological signs such as aphasia, blindness, and convulsions are often present.


 

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