The process of identifying various elements in tissue from a donor and comparing them to those of the recipient to see if a transplant is likely to be rejected.
The medical technique used in attempting to match organs and tissue for use in transplants; also called his-tocompatability testing.
Series of tests to determine the compatibility of tissues from a donor and a recipient before transplantation.
A laboratory test for identifying compatible tissue in prospective organ donors and recipients. Tissue-typing helps reduce the chances of organ rejection by closely matching the immune system of the donor to that of the recipient.
The essential procedure for matching the tissue of a recipient in need of transplanted tissue or organ to that of a potential donor. Unless there is a reasonable match, the recipient’s immune system will reject the donor’s organ. The main factors that are relevant to an individual’s reaction to donor tissue are called histo-compatability antigens. These are mostly human leucocyte antigens present on the surface of cells. HLAs are inherited and, like fingerprints, unique to an individual, although identical twins have identical HLAs and hence are perfect matches for transplantation procedures.
The determination of the human leukocyte antigens present on a cell or organ. Tissue typing is an essential element in matching proposed donors and recipients for organ transplantation.
The categorization of specific tissue traits in both potential organ donors and recipients aims to reduce the likelihood of the recipient’s immune system rejecting the transplanted organ.
An individual’s tissue type is determined based on their histocompatibility antigens, the most crucial of which are the human leukocyte antigens (HLAs) found on cell surfaces. These HLAs are inherited and unique to each person, although identical twins share the same set. Close family members often have similar, though not identical, HLA types.
In English, a person’s tissue type is determined through lab tests that analyze cells from a blood sample. One technique involves adding a special antiserum to the sample, which contains antibodies targeting a specific HLA. If that HLA is present, it will trigger a noticeable change, such as a color shift, to signal its detection.